Volume 17, Issue 2 (Mar-Apr 2023)                   mljgoums 2023, 17(2): 45-48 | Back to browse issues page

XML Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Jabbari A, Afghani R, Enayati A. Intraperitoneal Rupture of Infected Cyst in a Patient with Polycystic Kidney Disease after Kidney Transplant: A Case Report. mljgoums 2023; 17 (2) :45-48
URL: http://mlj.goums.ac.ir/article-1-1389-en.html
1- Ischemic Disorders Research Center, Golestan University of Medical Sciences, Gorgan, Iran , ali.jabbari2020@yahoo.com
2- Department of Surgery, 5Azar Hospital, Golestan University of Medical Science, Gorgan, Iran
3- Ischemic Disorders Research Center, Golestan University of Medical Sciences, Gorgan, Iran
Abstract:   (784 Views)
Background: Autosomal dominant polycystic kidney disease (ADPKD) is a multisystem disorder characterized by progressive renal cysts formation and extra-renal manifestations. Infection within the cysts and abscess formation are rare but life threatening if left untreated. We present a rare case of peritonitis presentation due to intraperitoneal rupture of an infected cyst in a woman with polycystic kidney disease.
Case description: A 42-year-old woman presented with constant progressing abdominal pain and vomiting. She complained of abdominal distention, bloating, and a change in bowel habits from two days ago. On physical examination, bilateral enlarged masses of flanks, generalized tenderness, and distention of the abdomen were found. The patient received conventional therapy. After appropriate fluid and electrolyte management and rescue care, appropriate antibiotics were prescribed, and laparotomy was performed. The rupture of an infected cyst of the right polycystic kidney into the peritoneal cavity was the cause of peritonitis in this patient. She successfully underwent a right radical nephrectomy (32×21cm, and 3,300 gr). The postoperative period was uneventful and the patient was discharged from the hospital after a week.
Conclusion: Antibiotic therapy is the first step in the treatment of renal cyst infection. When primary antibiotic therapy fails, drainage of the infected cyst is recommended. In medically fit patients for surgery and patients who present with complications of the infected cyst, radical surgery and nephrectomy is the procedure of choice. The best outcome is achieved after nephrectomy.
Full-Text [PDF 312 kb]   (276 Downloads) |   |   Full-Text (HTML)  (307 Views)  
Research Article: Case Report | Subject: Pathology
Received: 2021/06/2 | Accepted: 2021/09/8 | Published: 2023/03/14 | ePublished: 2023/03/14

References
1. Zahir M, Al Muttairi H, Upadhyay SP, Mallick PN. Rupture in polycystic kidney disease presented as generalized peritonitis with severe sepsis: a rare case report. Case Report in Urology. 2013;2013:Article ID 927676 [View at Publisher] [DOI:10.1155/2013/927676] [PubMed] [Google Scholar]
2. Torres VE, Harris PC, Pirson Y. Autosomal dominant polycystic kidney disease. Lancet. 2007 Apr 14;369(9569):1287-1301. [View at Publisher] [DOI:10.1016/S0140-6736(07)60601-1] [PubMed] [Google Scholar]
3. Desouza RM, Prachalias A, Srinivasan P, O'Doherty M, Olsburgh J. Differentiation between infection in kidney and liver cysts in autosomal dominant polycystic kidney disease: use of PET-CT in diagnosis and to guide management. Transplant Proc. 2009;41(5):1942-5. [View at Publisher] [DOI:10.1016/j.transproceed.2008.10.102] [PubMed] [Google Scholar]
4. Schwab SJ, Bander SJ, Klahr S. Renal infection in autosomal dominant polycystic kidney disease. Am J Med. 1987 Apr;82(4):714-8. [View at Publisher] [DOI:10.1016/0002-9343(87)90005-2] [PubMed] [Google Scholar]
5. Hammami M, Guirat A, Ksibi H, Azzaza M, Rekik N, Beyrouti MI. Intraperitoneal rupture of renal cyst in autosomal dominant polycystic kidney disease. North American journal of medical sciences. 2010;2(5):238-40. [PubMed] [Google Scholar]
6. Migali G, Annet L, Lonneux M, Devuyst O. Renal cyst infection in autosomal dominant polycystic kidney disease. Nephrology Dialysis Transplantation. 2008;23(1):404-5. [DOI:10.1093/ndt/gfm665]
7. Karuthu S, Blumberg EA. Common infections in kidney transplant recipients. Clin J Am Soc Nephrol. 2012; 7(12): 2058-70. [DOI:10.2215/CJN.04410512] [PubMed]
8. Lantinga MA, Casteleijn NF, Geudens A, de Sevaux RG, van Assen S, Leliveld AM, et al. Management of renal cyst infection in patients with autosomal dominant polycystic kidney disease: a systematic review. Nephrology Dialysis Transplantation. 2016;32(1):144-50. [View at Publisher] [DOI:10.1093/ndt/gfv452] [PubMed] [Google Scholar]
9. Suwabe T, Araoka H, Ubara Y, Kikuchi K, Hazue R, Mise K, et al. Cyst infection in autosomal dominant polycystic kidney disease: causative microorganisms and susceptibility to lipid-soluble antibiotics. European Journal of Clinical Microbiology Infectious Diseases. 2015;34(7):1369-79. [View at Publisher] [DOI:10.1007/s10096-015-2361-6] [PubMed] [Google Scholar]

Add your comments about this article : Your username or Email:
CAPTCHA

Send email to the article author


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2007 All Rights Reserved | Medical Laboratory Journal

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.