Volume 15, Issue 4 (Jul-Aug 2021)                   mljgoums 2021, 15(4): 6-8 | Back to browse issues page

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zakeri M, taheri F, rezanezhadi M, zaimy M A, Abdullah A L. A Case Report of a Man with Klinefelter Syndrome Having a Healthy Neonate with Normal Karyotype. mljgoums. 2021; 15 (4) :6-8
URL: http://mlj.goums.ac.ir/article-1-1325-en.html
1- Department of biology, Islamic Azad University, Tehran Medical Branch, Tehran, Iran , taheriforough93@gmail.com@yahoo.com
2- Sharekord Branch, Islamic Azad University, Sharekord, Iran
3- Master of microbiology, Kavosh medical laboratory , research and development unit,Gorgan, Iran
4- Department of Medeical Genetics, School of medicine, Tehran University of Medical Sciences, Tehran, Iran
5- General education in Baghdad, third Rusafa, Baghdad, Iraq
Abstract:   (210 Views)
Background: Klinefelter syndrome (KS) also known as 47, XXY is one of the most prevalent chromosomal abnormalities among men. Infertility is one of the most primary features of this condition. However, there are some other associated features such as thin and tall appearance, absent, delayed or incomplete puberty, small and firm testicles, small penis and gynecomastia.
Case description: We herein report a patient with mosaic KS whose karyotype consisted of 47, XXY/46, XY. The case’s wife had two miscarriages, followed by a healthy girl with a normal karyotype who was born taller than the average at the age of two.
Conclusion: Mosaic KS dramatically increases the chance of having healthy offspring with normal genetic patterns without performing artificial insemination methods compared to those with complete KS.
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Research Article: Brief Report | Subject: Microbiology
Received: 2020/07/12 | Accepted: 2020/08/15 | Published: 2021/06/30 | ePublished: 2021/06/30

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