Fri, Nov 22, 2024
Volume 11, Issue 5 (Sep - Oct 2017)
mljgoums 2017, 11(5): 22-26 |
Back to browse issues page
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Mohammadoghli Reihan Z, Ghiami Rad M, Sattari M. Frequency of Anti-Mycoplasma hominis Antibodies in Infertile Women Referred to Al-Zahra Hospital in Tabriz, Iran. mljgoums 2017; 11 (5) :22-26
URL: http://mlj.goums.ac.ir/article-1-1015-en.html
URL: http://mlj.goums.ac.ir/article-1-1015-en.html
1- Microbiology Department, Faculty of Basic science, Islamic Azad University Ahar branch, Ahar, Iran , Zahra_Reyhan@yahoo.com
2- Department of microbiology, Faculty of science, Islamic Azad university Ahar branch, Ahar, Iran
3- Microbiology Department, Faculty of Basic science, Islamic Azad University Ahar branch, Ahar, Iran
2- Department of microbiology, Faculty of science, Islamic Azad university Ahar branch, Ahar, Iran
3- Microbiology Department, Faculty of Basic science, Islamic Azad University Ahar branch, Ahar, Iran
Abstract: (11421 Views)
ABSTRACT
Background and Objectives: Infertility is one of the important causes of anxiety in couples. Infections caused by genital Mycoplasmas may have harmful effects on the reproductive health of women, and sometimes lead to infertility. This study was designed to determine frequency of anti-Mycoplasma hominis antibodies in infertile women at Al-Zahra Hospital, Tabriz, Iran.
Methods: In this cross-sectional study, serum from 184 infertile women and 100 healthy pregnant women were tested for presence of M. hominis IgM and IgG antibodies by ELISA. Data collected were analyzed in SPSS (version 17) using t-test at significance level of 0.05.
Results: The frequency of anti-M. hominis IgG was significantly higher in infertile women compared to healthy controls. The frequency of anti-M. hominis IgM did not differ significantly between the infertile and control subjects. The majority of the women infected with the bacterium were in the 21-30 and 31-40 years age range. There was no significant correlation between tubal factor infertility and seropositivity for M. hominis antibodies. Moreover, the dwelling of the participants had no relationship with the frequency of anti-M. hominis antibodies.
Conclusion: The frequency of owed that a high percentage of t a high percentage of that the meaninngful le women was 4% and infertile women infected with this bacterium is high in Tabriz. Therefore, it is important to perform microbial screening for this bacterium in infertile couples.
Keywords: Mycoplasma hominis, Infertility, Women, Tabriz.
ABSTRACT
Background and Objectives: Infertility is one of the important causes of anxiety in couples. Infections caused by genital Mycoplasmas may have harmful effects on the reproductive health of women, and sometimes lead to infertility. This study was designed to determine frequency of anti-Mycoplasma hominis antibodies in infertile women at Al-Zahra Hospital, Tabriz, Iran.
Methods: In this cross-sectional study, serum from 184 infertile women and 100 healthy pregnant women were tested for presence of M. hominis IgM and IgG antibodies by ELISA. Data collected were analyzed in SPSS (version 17) using t-test at significance level of 0.05.
Results: The frequency of anti-M. hominis IgG was significantly higher in infertile women compared to healthy controls. The frequency of anti-M. hominis IgM did not differ significantly between the infertile and control subjects. The majority of the women infected with the bacterium were in the 21-30 and 31-40 years age range. There was no significant correlation between tubal factor infertility and seropositivity for M. hominis antibodies. Moreover, the dwelling of the participants had no relationship with the frequency of anti-M. hominis antibodies.
Conclusion: The frequency of owed that a high percentage of t a high percentage of that the meaninngful le women was 4% and infertile women infected with this bacterium is high in Tabriz. Therefore, it is important to perform microbial screening for this bacterium in infertile couples.
Keywords: Mycoplasma hominis, Infertility, Women, Tabriz.
Background and Objectives: Infertility is one of the important causes of anxiety in couples. Infections caused by genital Mycoplasmas may have harmful effects on the reproductive health of women, and sometimes lead to infertility. This study was designed to determine frequency of anti-Mycoplasma hominis antibodies in infertile women at Al-Zahra Hospital, Tabriz, Iran.
Methods: In this cross-sectional study, serum from 184 infertile women and 100 healthy pregnant women were tested for presence of M. hominis IgM and IgG antibodies by ELISA. Data collected were analyzed in SPSS (version 17) using t-test at significance level of 0.05.
Results: The frequency of anti-M. hominis IgG was significantly higher in infertile women compared to healthy controls. The frequency of anti-M. hominis IgM did not differ significantly between the infertile and control subjects. The majority of the women infected with the bacterium were in the 21-30 and 31-40 years age range. There was no significant correlation between tubal factor infertility and seropositivity for M. hominis antibodies. Moreover, the dwelling of the participants had no relationship with the frequency of anti-M. hominis antibodies.
Conclusion: The frequency of owed that a high percentage of t a high percentage of that the meaninngful le women was 4% and infertile women infected with this bacterium is high in Tabriz. Therefore, it is important to perform microbial screening for this bacterium in infertile couples.
Keywords: Mycoplasma hominis, Infertility, Women, Tabriz.
ABSTRACT
Background and Objectives: Infertility is one of the important causes of anxiety in couples. Infections caused by genital Mycoplasmas may have harmful effects on the reproductive health of women, and sometimes lead to infertility. This study was designed to determine frequency of anti-Mycoplasma hominis antibodies in infertile women at Al-Zahra Hospital, Tabriz, Iran.
Methods: In this cross-sectional study, serum from 184 infertile women and 100 healthy pregnant women were tested for presence of M. hominis IgM and IgG antibodies by ELISA. Data collected were analyzed in SPSS (version 17) using t-test at significance level of 0.05.
Results: The frequency of anti-M. hominis IgG was significantly higher in infertile women compared to healthy controls. The frequency of anti-M. hominis IgM did not differ significantly between the infertile and control subjects. The majority of the women infected with the bacterium were in the 21-30 and 31-40 years age range. There was no significant correlation between tubal factor infertility and seropositivity for M. hominis antibodies. Moreover, the dwelling of the participants had no relationship with the frequency of anti-M. hominis antibodies.
Conclusion: The frequency of owed that a high percentage of t a high percentage of that the meaninngful le women was 4% and infertile women infected with this bacterium is high in Tabriz. Therefore, it is important to perform microbial screening for this bacterium in infertile couples.
Keywords: Mycoplasma hominis, Infertility, Women, Tabriz.
Research Article: Original Paper |
Received: 2017/11/15 | Accepted: 2017/11/15 | Published: 2017/11/15 | ePublished: 2017/11/15
Received: 2017/11/15 | Accepted: 2017/11/15 | Published: 2017/11/15 | ePublished: 2017/11/15
References
1. Rosemond A, Lanotte P, Watt S, Sauget AS, Guerif F, Royere D, et al. Systematic Screening Tests for Chlamydia Trachomatis, Mycoplasma Hominis and Ureaplasma Urealyticum in Urogenital Specimens Of Infertile Couples. Pathol Biol 2006; 54(3): 125-29. doi: 10.1016/j.patbio.2005.09.004. [DOI:10.1016/j.patbio.2005.09.004]
2. Bayley TM, Slade P, Lashen H. Relationships between attachment, appraisal, coping and adjustment in men and women experiencing infertility concerns. Human Reproduction. 2009; 24(11): 2827-2837. doi:10.1093/humrep/dep235 [DOI:10.1093/humrep/dep235]
3. Faria DEP, Grieco SC, Barros SMO. The effects of infertility on the spouses' relationship. Rev Esc Enferm USP. 2012; 46(4): 794-801. PubMed: 23018385. [DOI:10.1590/S0080-62342012000400002]
4. Tabong P, Adongo P. Nfertility and childlessness: a qualitative study of the experiences of infertile couples in Northern Ghana. BMC Pregnancy and Childbirth. 2013; 13: 17. doi:10.1186/1471-2393-13-72. [DOI:10.1186/1471-2393-13-72]
5. Nojomi M, Ashrafi M, Kohpayezadeh J. Prevalence of couples infertility in the west of Tehran in 2001. J Medical Sci. 2001; 8(21): 633-40.
6. Akbari S, Vahabi S, Kazwmi AH. Knowledge of working women in Hospitals of Lorestan Medical Sciences University about smoking effects on fertility. J Reproduction and infertility. 2002; 3(3): 59-64.
7. Najar peerayeh Sh, Samimi R. Comparision Of Culture With The Polymerase Chain Reaction For Detection Of Genital Mycoplasma. Eur J Gen Med. 2008; 5(2): 107-111. [DOI:10.29333/ejgm/82587]
8. Serin MS, Evruke C, Kibar F, Koksal F. Comparison of PCR and cultivation methods to determine the incidence of infections due to mycoplasma hominis and mycoplasma fermentans in women genitourinary tract. Eastern Journal of Medicine. 2001; 6(2): 48-52. Vosogi S, Kheirkhah B, Kariminik A, Mirshekari TR. Review the role of Mycoplasma infections in humans infertility. J Cellular-Molecular Biotechnology News. 2012; 2(8): 9-20.
9. Baczynska A, Svenstrup H, Fedder J, Birkelund S, Christianse G. Development of real-time PCR for detection of Mycoplasma hominis. BMC Microbiol. 2004; 4: 35-43. doi:10.1186/1471-2180-4-35. [DOI:10.1186/1471-2180-4-35]
10. Chigumadzi PT, Moodley J, Bagratee J. Infertility Profile at King Edward VIII Hospital, Durban, South Africa. Trop Doc. 1998; 28(3): 168-172. [DOI:10.1177/004947559802800314]
11. Schachter J. Chlamydia infection. N Eng J Med. 1978; 298: 428. [DOI:10.1056/NEJM197802232980805]
12. Westrom L. Incidence: Effect of acute inflammatory disease on fertility. Am J Obstet Gynecol. 1975; 121(5): 707-13. [DOI:10.1016/0002-9378(75)90477-9]
13. Najarpiraye Sh, Alyasin A. Comparison of PCR and culture for the detection of Mycoplasma hominis in infertile women. Kowsar Medical J. 2005; 10(3): 183-190.
14. Salari M, Samimi R. Mycoplasma hominis and Ureaplasma urealyticum in infertile women compared to the control group]. Hakim Research J 2000; (4): 322-326.
15. Surana A, Rastogi V, Nirwan PS. Association of the serum anti-Chlamydial antibodies with tubal infertility. J Clin Diagn Res 2012; 6: 1692-1694. doi: 10.7860/JCDR/2012/3771.2632. [DOI:10.7860/JCDR/2012/3771.2632]
16. Fanaei H, Mardaneh J, Khayat S. An overview of the role of bacterial infections in male infertility. J Fasa Medical Sci. 2012; 2(4): 227-234.
17. Miron ND, Socolov D, Mareş M, Anton G, Nastasa V, Moraru RF, et al. Bacteriological agents which play a role in the development of infertility. Acta Microbiol Immunol Hung. 2013; 60(1): 41-53. doi:10.1556/AMicr.60.2013.1.5. [DOI:10.1556/AMicr.60.2013.1.5]
18. Günyeli I, Abike F, Dünder I, Aslan C, Tapısız OL, Temizkan O, et al. Chlamydia, Mycoplasma and Ureaplasma infections in infertile couples and effects of these infections on fertility. Arch Gynecol Obstet. 2011; 283(2): 379-85. doi:10.1007/s00404-010-1726-4. [DOI:10.1007/s00404-010-1726-4]
19. Grześko J, Elias M, Maczyńska B, Kasprzykowska U, Tłaczała M, Goluda M. Frequency of detection of Ureaplasma urealyticum and Mycoplasma hominis in cervical canal and the Douglas pouch of infertile and fertile women. Med Dosw Mikrobiol. 2007; 59(2): 169-75. PMID: 17929414.
20. Reid I, Martinez MA, Biron M, Aceituno R. Mycoplasma hominis and Ureaplasma urealyticum in pregnant and infertile women. Differences in tubal pathology. Rev Chil Obstet Ginecol. 1993; 58(5): 349-54. PMID: 7991855.
21. Ahmadi MH, Mozafari NA, Sedigi MA, Kazemi B, Masjedianjezi F. Comparison of culture and PCR in identification of Mycoplasma hominis and Ureaplasma urealyticum from semen samples of infertile men referred to Royan institute in 2009. J Medical Sci. 2009; 17(76): 15-29.
22. Baczynska A, Friis Svenstrup H, Fedder J, Birkelund S, Christiansen G. The use of enzyme-linked immunosorbent assay for detection of Mycoplasma hominis antibodies in infertile women serum samples. Hum Reprod. 2005; 20(5): 1277-85. doi:10.1093/humrep/deh780. [DOI:10.1093/humrep/deh780]
23. Costoya A, Morales F, Borda P, Vargas R, Fuhrer J, Salgado N, et al. Mycoplasmateceae species are not found in Fallopian tubes of women with tubo-peritoneal infertility. Infectious Diseases. 2012; 16(3): 273-278. PMID: 22729196.
Send email to the article author
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
Enamad
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.