Volume 16, Issue 6 (Special issue (Nov-Dec) 2022)                   mljgoums 2022, 16(6): 1-7 | Back to browse issues page


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Zope R, Kate P, Jaison J, Saraf S, Bhide S, Gupta D. Evaluation of WBC Parameters and Their Significance in COVID-19 Patients in Western Maharashtra, India. mljgoums 2022; 16 (6) :1-7
URL: http://mlj.goums.ac.ir/article-1-1581-en.html
1- Department of Pathology, MAEER MIT Pune’s MIMER Medical College & Dr. B.S.T.R. Hospital, Talegaon Dabhade. Tal. Maval, Dist. Pune. Pin code – 410507 State – Maharashtra. Country – India
2- Tutor, Department of Pathology, MAEER MIT Pune’s MIMER Medical College & Dr. B.S.T.R. Hospital, Talegaon Dabhade. , prachiskate@yahoo.co.in
3- Department of Clinical Research and Incubation Center. MAEER MIT Pune’s MIMER Medical College & Dr. B.S.T.R. Hospital, Talegaon Dabhade. Tal. Maval, Dist. Pune. Pin code – 410507 State – Maharashtra. Country – India
Abstract:   (1933 Views)
Background and objectives: In patients with coronavirus disease 2019 (COVID-19), white blood cell (WBC) abnormalities have been found worldwide with significant inter-regional differences. In the present study, we evaluated WBC parameters concerning COVID-19 positivity and severity.
Methods: In this cross-sectional study, total WBC count, absolute count of each type of WBC, neutrophil to lymphocyte ratio (NLR), and lymphocyte to monocyte ratio (LMR) were compared between 150 COVID-19 patients and 150 non-COVID-19 patients presenting with COVID-19-like symptoms. Also, COVID-19 patients were divided into severe and non-severe cases.
Results: The severity of the disease had no significant association with age or gender (p>0.05). Total WBC count, absolute neutrophil count, absolute monocyte count, and NLR were significantly lower (p<0.05), while LMR was significantly higher in COVID-19 patients compared to non-COVID-19 patients (p<0.05). Total WBC count, absolute neutrophil count, and NLR were significantly higher (p<0.05), while absolute eosinophil count and absolute lymphocyte count were significantly lower (p<0.05) in severe COVID-19 patients compared to non-severe patients.
Conclusions: Age is not a predictive factor for the severity of COVID-19. Routine WBC parameters are useful in predicting the severity of the disease in COVID-19 patients and can be used as prognostic indicators. Routine WBC parameters can also be used for repeat RT-PCR testing in COVID-19 suspected patients.

 
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Research Article: Original Paper | Subject: Pathology
Received: 2022/10/13 | Accepted: 2022/12/10 | Published: 2022/11/28 | ePublished: 2022/11/28

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