Volume 13, Issue 4 (Jul-Aug 2019)                   mljgoums 2019, 13(4): 14-16 | Back to browse issues page

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Khandandel A, Kaboosi H, Jamalli A, Peyravii Ghadikolaii F. Evaluation of Biofilm Formation in Staphylococcus aureus Clinical Isolates. mljgoums. 2019; 13 (4) :14-16
URL: http://mlj.goums.ac.ir/article-1-1220-en.html
1- Department of Microbiology, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran
2- Laboratory Sciences Research Center, Golestan University of Medical Sciences, Gorgan, Iran
3- Department of Biology, Ghaemshahr Branch, Islamic Azad University, Ghaemshahr, Iran
Abstract:   (3529 Views)
          Background and Objectives: Staphylococcus aureus is a common cause of nosocomial infections. The ability of S. aureus to form biofilm and acquire antimicrobial resistance has made this organism a major health problem. In this study, we investigate the biofilm-forming ability of S. aureus isolates from clinical samples.
          Methods: Sixty S. aureus isolates from clinical specimens were collected from the 5th Azar Hospital of Gorgan (Iran) in 2018. The isolates were identified using conventional methods including Gram staining and biochemical tests (catalase and coagulase). Biofilm formation by S. aureus isolates was evaluated using a microplate-based method.
          Results: Of 60 S. aureus isolates, 47 (78.3%) strains were identified as biofilm-forming and 13 (21.7%) strains were non-biofilm-forming.
          Conclusion: The high prevalence of biofilm-producing S. aureus isolates in the 5th Azar hospital of Gorgan could pose a major health challenge with serious consequences for hospitalized patients. Therefore, it is crucial to disinfect and sterilize hospital surfaces and equipment effectively to minimize the risk of contamination and spread of bacteria in the hospital settings.
          Keywords: Biofilms, Staphylococcus aureus, sample.
Full-Text [PDF 500 kb]   (865 Downloads)    
Type of Study: Review Article | Subject: Parasitology
Received: 2019/05/22 | Accepted: 2019/05/22 | Published: 2019/05/22 | ePublished: 2019/05/22

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