Volume 7, Issue 3 (Autumn 2013)
mljgoums 2013, 7(3): 24-30 |
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S Royani1 
, S Alijanpor2 , Z Shirbaghaei3 , R Khorasaninejad4 , GH Roshandel5 , AA Ayatollahi6 , HR Joshaghani 7
, S Alijanpor2 , Z Shirbaghaei3 , R Khorasaninejad4 , GH Roshandel5 , AA Ayatollahi6 , HR Joshaghani 7
1- BSc of Nursing and MSc of Strategic Management, Medical Laboratory Kavosh
2- MSc student of Genetics, Golestan University of Medical Sciences
3- Msc Student of Immunology, Tehran University of Medical Sciences
4- Student of Medicine, School of Medicine, Golestan University of Medical Sciences
5- PhD Student of Epidemiology, Research Center of Gastroenterology and Hepatology, Golestan University of Medical Sciences
6- Medical Doctor of Laboratory, Laboratory Sciences Research Center, Golestan University of Medical Sciences
7- Associated Professor of Biochemistry, Research Center of Gastroenterology and Hepatology, Golestan University of Medical Sciences , hr_joshaghani@yahoo.com
2- MSc student of Genetics, Golestan University of Medical Sciences
3- Msc Student of Immunology, Tehran University of Medical Sciences
4- Student of Medicine, School of Medicine, Golestan University of Medical Sciences
5- PhD Student of Epidemiology, Research Center of Gastroenterology and Hepatology, Golestan University of Medical Sciences
6- Medical Doctor of Laboratory, Laboratory Sciences Research Center, Golestan University of Medical Sciences
7- Associated Professor of Biochemistry, Research Center of Gastroenterology and Hepatology, Golestan University of Medical Sciences , hr_joshaghani@yahoo.com
Abstract: (40470 Views)
Abstract
Background and Objective: Of the most common hypochromic microcytic anemia are iron deficiency anemia and minor thalassemia, which are common in Iran and their differential diagnosis is extremely important. The level of 25-hydroxy vitamin D is the indication of vitamin D blood status. The aim of this study was to compare serum levels of vitamin D in people with minor thalassemia and iron deficiency anemia with healthy subjects in order to investigate the relationship between vitamin D deficiency and iron absorption.
Material and Methods: In this case-control study, 24 patients with minor thalassemia, 20 patients with iron deficiency anemia and 24 healthy individuals participated. Groups were matched for age and sex. Testing of Vitamin D level by ELISA, ferritin by quantitative luminescence method and HbA2 by column chromatography was carried out.
Results: The number of individuals with low level of vitamin D in iron deficiency group is 15 (75%), in minor thalassemia group is 8 (33/3%) and in the control group 11 (45.8%).
Conclusion: In this study, the highest percentage of vitamin D deficiency is observed in cases with iron deficiency anemia. Because of association between vitamin D and anemia, iron and vitamin D supplementation is recommended to enrich the diet.
Keywords: Anemia Minor Thalassemia Iron Deficiency Anemia Vitamin D
Research Article: Original Paper |
Received: 2013/08/18 | Accepted: 2013/09/29 | Published: 2013/09/29 | ePublished: 2013/09/29
Received: 2013/08/18 | Accepted: 2013/09/29 | Published: 2013/09/29 | ePublished: 2013/09/29
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