Volume 10, Issue 6 (Nov-Dec-2016 2016)                   mljgoums 2016, 10(6): 32-37 | Back to browse issues page

XML Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Abbassi Daloii A, Mousavi E. Effect of 8-week Aerobic Exercise on Undercarboxylated Osteocalcin and Beta Cell Function in Postmenopausal Women. mljgoums 2016; 10 (6) :32-37
URL: http://mlj.goums.ac.ir/article-1-918-en.html
Effect of 8-week Aerobic Exercise on Undercarboxylated Osteocalcin and Beta Cell Function in Postmenopausal Women
Asieh Abbassi Daloii 1, Esmatalsadat Mousavi2
1- Department of Sport Physiology Islamic Azad University , abbasi.daloii@gmail.com
2- Department of Sport Physiology Islamic Azad University
Abstract:   (14455 Views)

ABSTRACT

          Background and Objective: The present study aims at investigating the possible effect of 8-week aerobic exercise on undercarboxylated osteocalcin and beta cell function in postmenopausal women.

         Methods: The study included 20 postmenopausal women with mean weight, height and body mass index of 78.94 ± 5.72 kg, age 48.69 ± 3.21 years, 160.37 ± 4.12 cm and 30.72 ± 2.37 kg/m2. The participants were randomly selected and divided into experimental and control groups. Blood samples were taken 48 hours before the experiment and after eight weeks of exercise. Aerobic exercise was performed for eight weeks, three sessions per week with intensity of 65-70% of heart rate. Data analysis for intragroup and intergroup differences was done using paired and independent t-test, respectively. P-values less than 0.05 were considered statistically significant.            

         Results: The level of undercarboxylated osteocalcin in the experimental group decreased significantly compared to control group (P<0.049). The level of beta cell function index in the experimental group increased significantly after the 8-week exercise program compared to  control group (P<0.014).

         Conclusion: Exercise increases the level of undercarboxylated osteocalcin in postmenopausal women that has important consequences, especially for those at risk of developing diabetes.

            Keywords: Exercise, Osteocalcin, Hemoglobin A, Glycosylated, Postmenopause.

Keywords: Exercise, Osteocalcin, Hemoglobin A, Glycosylated, Postmenopause.
Full-Text [PDF 458 kb]   (1639 Downloads)    
Research Article: Original Paper |
Received: 2016/01/25 | Accepted: 2016/01/25 | Published: 2016/09/25 | ePublished: 2016/09/25
References
1. De Graaf DC, Vanopdenbosch E, Ortega-Mora LM, Abbassi H, Peeters JE. A review of the importance of cryptosporidiosis in farm animals. Int J Parasitol.1999; 29(8):1269-1287. [DOI:10.1016/S0020-7519(99)00076-4]
2. Santin M, Trout JM, Xiao L, Zhou L, Greiner E, Fayer R. Prevalence and age-related variation of Cryptosporidium species and genotypes in dairy calves. Vet Parasitol. 2004; 122(2): 103-117. [DOI:10.1016/j.vetpar.2004.03.020]
3. Petersen C. Cryptosporidiosis in patients infected with the human immunodeficiency virus. Clin Infect Dis.1992; 15(6): 903-909. [DOI:10.1093/clind/15.6.903]
4. Jenkins MC, D' Brien C, Trout J, Guidry A, Fayer R. Hyperimmune bovine colostrum specific for recombinant Cryptosporidium parvum antigen confers partial protection against cryptosporidiosis in immunosuppressed adult mice. Vaccine.1998; 17(19): 2453-2460. [DOI:10.1016/S0264-410X(98)00369-7]
5. Xiao L, Fayer R, Ryan V, Upton SJ. Cryptosporidium Taxonomy: Recent Advances and Implication for public health. Clin Microbial Rev. 2004; 17(1): 72-79. [DOI:10.1128/CMR.17.1.72-97.2004]
6. Fayer R. Cryptosporidium and cryptosporidiosis. CRC, New York. 1997.
7. Perryman L E, Kegerries K A, Mason P H. Effect of orally administered monoclonal antibody on persistent Cryptosporidium parvum infection in SCID mice. Infect Immun. 1993; 61(11): 4906-8.
8. Martı’n-Go’mez S, A’lvarez-Sa’nchez M A, Rojo-Va’zquez F A. Immunization protocols against Cryptosporidium parvum in ovines: protection in suckling lambs. Vet Parasitol. 2005; 129(1-2): 11-20. [DOI:10.1016/j.vetpar.2004.11.033]
9. Kobayashi C, Yokoyama H, Neguyen S A, Kodama Y, Kimata T, Izeki M. Effect of egg yolk antibody on experimental cryptosporidium parvum infection in mice. Vaccine. 2004; 23(2): 232-235. [DOI:10.1016/j.vaccine.2004.05.034]
10. Kuroki M, Ohta M, Ikemori Y, Peralta R C, Yokoyama H, Kodama Y. Passive protection against bovine rotavirus in calves by specific immunoglobulins from chicken egg yolk. Arch Virol. 1994; 138(1): 143-148. [DOI:10.1007/BF01310045]
11. Mine Y, Kovacs-Nolan J. Chicken Egg yolk antibodies as therapeutics in enteric infectious disease. J Med food. 2002; 5 (3): 159-166. [DOI:10.1089/10966200260398198]
12. Ruan GP, Ma L, He XW, Meng MJ, Zhou MQ, Hu ZM, et al. Efficient production, purification, and application of egg yolk antibodies against human HLA-A*0201 heavy chain and light chain (β2m). Prot Exp and Purific. 2005; 44(1): 45-51. [DOI:10.1016/j.pep.2005.03.013]
13. Larsson A, Sjöquist J. Chicken IgY: utilizing the evolutionary difference. Comp Immunol Microbiol Infect Dis. 1990; 13(4):199-201. [DOI:10.1016/0147-9571(90)90088-B]
14. Bizanov G, Normantine T, Jonauskiene I. Development of antibodies to Sendai virus in chickens and their isolation from yolk. Biologi J A. 2006; 2: 68-71
15. Arrowed MJ, Sterling CR. Comparison of conventional staining methods and monoclonal antibody-based method for Cryptosporidium oocyst detection. J Clin Microbiol. 1989; 27(7): 1490-1495.
16. Lorenzo MJ, Ares-Mazas E, villacorta Martinez de Maturana I. Detection of oocysts and IgG antibodies to Cryptosporidium parvum in asymptomatic adult cattle. Vet Parasitol. 1993; 47(1-2): 9-15. [DOI:10.1016/0304-4017(93)90171-I]
17. Bizanov G, Jonauskiene I. Production and purification of IgY from egg yolk after immunization of hens with pig IgG. Bull Vet Inst Pulawy. 2003; 47(2): 403-410.
18. Tini M, Jewel UR, Camendish G, Chilov D, Cassmann M. Generation and application of chicken egg-yolk antibodies. Comp Biochem Physiol A Mol Integr Physiol. 2002; 131: 569-574. [DOI:10.1016/S1095-6433(01)00508-6]
19. Harp JA, Goff JP. Protection of calves with a vaccine against Cryptosporidium parvum. J Parasitol. 1995; 81(1): 54-57. [DOI:10.2307/3284005]
20. Nord J, Ma P, Dijohn D, Tzipori S, Tacket CO. Treatment with bovine hyper immune colostrums of Cryptosporidial diarrhea in AIDS patients. AIDS. 1990; 4(6): 581-584. [DOI:10.1097/00002030-199006000-00015]
21. Perryman LE, Kapil SJ, Jones ML, Hunt EL. Protection of calves against cryptosporidiosis with immune bovine colostrum induced by a Cryptosporidium parvum recombinant protein. Vaccine. 1999; 17(17): 2142-2149. [DOI:10.1016/S0264-410X(98)00477-0]
22. Reperant J M, Naciri M, Iochmann S, Tilley M, Bout DT. Major antigens of Cryptosporidium parvum recognized by serum antibodies from different infected animal species and man. Vet Parasitol. 1994; 55(1-2): 1-13. [DOI:10.1016/0304-4017(94)90051-5]
23. Shayan P, Ebrahimzade E. Recombinant Cryptosporidium parvum P23 as a target for the detection of cryptosporidium- specific antibody in calf sera. Parasitol Res. 2008; 103(5): 1207-1211. doi: 10.1007/s00436-008-1117-y. [DOI:10.1007/s00436-008-1117-y]
24. Riggs MW, Cama VA, Leary HL, Sterling CR. Bovine antibody against Cryptosporidium parvum elicits a circumsporozoite precipitate-like reaction and has immunotherapeutic effect against persistent cryptosporidiosis in SCID mice. Infect Immun. 1994; 62(5): 1927-1939.
Add your comments about this article : Your username or Email:
CAPTCHA
Send email to the article author

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2007 All Rights Reserved | Medical Laboratory Journal

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.