XML Print


1- Department of Microbiology, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, Iran.
2- Department of Microbiology, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, Iran. & Infectious Research Center, Golestan University of Medical Sciences, Gorgan, Iran
3- Department of Microbiology, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, Iran. , tabarraei@goums.ac.ir
Abstract:   (935 Views)
Introduction:
Congenital cytomegalovirus (cCMV) is the most common congenital infection worldwide, often causing long-term disabilities such as sensorineural hearing loss and developmental delays. Despite its significant public health impact, awareness of cCMV among healthcare providers in developing countries, like Iran, remains notably low.

Methods:
This study builds on prior research highlighting a significant knowledge gap about cCMV among family physicians in Iran. A re-analysis of existing data was conducted to better understand these gaps and to identify where targeted educational interventions might be most effective. The study reassessed data using 11 out of 15 questionnaire questions to evaluate awareness of CMV, categorizing participants into three levels: weak, intermediate, and adequate awareness based on their knowledge of CMV and cCMV.
Results:
Results showed that while 41.9% of participants had adequate general knowledge of CMV, only 32.8% demonstrated adequate knowledge of cCMV, with 39.4% showing weak awareness. Notably, 42.1% of general practitioners displayed a weak understanding of cCMV, underscoring the need for improved education. In contrast, specialists had a higher awareness of general CMV but showed reduced knowledge about cCMV.
Conclusions:
The study recommends the integration of comprehensive educational programs into medical curricula and continuous professional development for both general practitioners and specialists. Addressing these knowledge gaps is critical to reducing the spread of cCMV and its associated social and economic burdens, ultimately improving public health outcomes.
Full-Text [PDF 304 kb]   (231 Downloads)    
Research Article: Research Article | Subject: Virology
Received: 2024/09/17 | Accepted: 2024/11/30

References
1. Boyle M, Posada R. Congenital Cytomegalovirus. Pediatrics In Review. 2022;43(5):291-3. [View at Publisher] [DOI] [Google Scholar]
2. Yasaghi M, Hosseini SD, Moradi A, Hassanpour M, Tabarraei A. Molecular detection of HHV-1, HHV-2, HHV-5 and HBV in semen of fertile and infertile men by multiplex PCR method. Iran J Microbiol. 2022;14(6):921-7. [View at Publisher] [DOI] [PMID] [Google Scholar]
3. Adler SP. Screening for cytomegalovirus during pregnancy. Infect Dis Obstet Gynecol. 2011:2011:1-9 [View at Publisher] [DOI] [PMID] [Google Scholar]
4. Adler SP, Finney JW, Manganello AM, Best AM. Prevention of child-to-mother transmission of cytomegalovirus among pregnant women. J Pediatr. 2004;145(4):485-91. [View at Publisher] [DOI] [PMID] [Google Scholar]
5. Sartori P, Baud D, de Tejada BM, Farin A, Rossier M-C, Rieder W, et al. Cytomegalovirus infection during pregnancy: cross-sectional survey of knowledge and prevention practices of healthcare professionals in French-speaking Switzerland. Virol J. 2024;21(1):45. [View at Publisher] [DOI] [PMID] [Google Scholar]
6. Hosseinzadeh Adli A, Karami C, Baghban Rahimi S, Mirarab A, Tabarraei A. What family doctors know about congenital CMV: a regional survey in Iran. Ital J Pediatr. 2018;44(1):31. [View at Publisher] [DOI] [PMID] [Google Scholar]
7. Liberati C, Sturniolo G, Brigadoi G, Cavinato S, Visentin S, Cosmi E, et al. Burden of Congenital CMV Infection: A Narrative Review and Implications for Public Health Interventions. Viruses. 2024;16(8):1311. [View at Publisher] [DOI] [PMID] [Google Scholar]
8. Pesch MH, Saunders NA, Abdelnabi S. Cytomegalovirus infection in pregnancy: prevention, presentation, management and neonatal outcomes. J Midwifery Womens Health. 2021;66(3):397-402. [View at Publisher] [DOI] [PMID] [Google Scholar]
9. Azadfar S, Yamchi A, Majd A, Tabarraei A. Expression and purification of HCMV glycoprotein B full protein in Escherichia coli. JCMR. 2020;11(3):60. [View at Publisher] [DOI] [Google Scholar]
10. Plotogea M, Isam AJ, Frincu F, Zgura A, Bacinschi X, Sandru F, et al. An overview of cytomegalovirus infection in pregnancy. Diagnostics (Basel). 2022;12(10):2429. [View at Publisher] [DOI] [PMID] [Google Scholar]
11. Sapuan S, Theodosiou AA, Strang BL, Heath PT, Jones CE. A systematic review and meta‐analysis of the prevalence of human cytomegalovirus shedding in seropositive pregnant women. Rev Med Virol. 2022;32(6):e2399. [View at Publisher] [DOI] [PMID] [Google Scholar]
12. Okahashi A, Kobayashi M, Okuyama K, Hiraishi N, Morioka I. Survey of physician knowledge of congenital cytomegalovirus infection and clinical practices in Japan: A web-based survey. Medicine (Baltimore). 2021;100(44):e27589. [View at Publisher] [DOI] [PMID] [Google Scholar]
13. Boucoiran I, Yudin M, Poliquin V, Caddy S, Gantt S, Castillo E. Guideline no. 420: cytomegalovirus infection in pregnancy. J Obstet Gynaecol Can. 2021;43(7):893-908. [View at Publisher] [DOI] [PMID] [Google Scholar]
14. Fellah T, Sibiude J, Vauloup-Fellous C, Cordier AG, Guitton S, Grangeot-Keros L, et al. Evolution of awareness and knowledge of congenital cytomegalovirus infection among health care providers in France between 2011 and 2018. J Clin Virol. 2020;129:104335. [View at Publisher] [DOI] [PMID] [Google Scholar]
15. Balegamire SJ, McClymont E, Croteau A, Dodin P, Gantt S, Besharati AA, et al. Prevalence, incidence, and risk factors associated with cytomegalovirus infection in healthcare and childcare worker: a systematic review and meta-analysis. Syst Rev. 2022;11(1):131. [View at Publisher] [DOI] [PMID] [Google Scholar]
16. Balegamire SJ, Renaud C, Mâsse B, Zinszer K, Gantt S, Giguere Y, et al. Frequency, timing and risk factors for primary maternal cytomegalovirus infection during pregnancy in Quebec. PLoS One. 2021;16(6):e0252309. [View at Publisher] [DOI] [PMID] [Google Scholar]
17. Nicloux M, Peterman L, Parodi M, Magny J-F. Outcome and management of newborns with congenital cytomegalovirus infection. Arch Pediatr. 2020;27(3):160-5. [View at Publisher] [DOI] [PMID] [Google Scholar]

Add your comments about this article : Your username or Email:
CAPTCHA

Send email to the article author


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.