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mljgoums 2023, 17(5): 9-11 |
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Younesian O, Khodabakhshi B, Hosseinzadeh S, Hosseini Alarzi S S, Younesian S, Pourmomen M, et al . The impact of the sputnik v vaccine on antibody responses in the general population of Golestan province, Iran. mljgoums 2023; 17 (5) :9-11
URL: http://mlj.goums.ac.ir/article-1-1531-en.html
URL: http://mlj.goums.ac.ir/article-1-1531-en.html
Ommolbanin Younesian1 
, Behnaz Khodabakhshi2 , Sara Hosseinzadeh3 , Seyedeh Somayeh Hosseini Alarzi4 , Samareh Younesian5 , Mojtaba Pourmomen6 , Mana Zakeri7 , Ali Hosseini8 , Hamidreza Joshaghani 9
, Behnaz Khodabakhshi2 , Sara Hosseinzadeh3 , Seyedeh Somayeh Hosseini Alarzi4 , Samareh Younesian5 , Mojtaba Pourmomen6 , Mana Zakeri7 , Ali Hosseini8 , Hamidreza Joshaghani 9
1- Metabolic Disorders Research Center, Golestan University of Medical Sciences, Gorgan, Golestan province, Iran
2- Infectious Diseases Research Center, Golestan University of Medical Sciences, Gorgan, Iran
3- Laboratory Sciences Research Center, Golestan University of Medical Sciences, Gorgan, Iran
4- Department of Medical Biotechnology, School of Allied Medical Sciences, Iran University of Medical Sciences, Tehran, Iran
5- Department of Hematology and Blood Banking, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran
6- Department of Microbiology, Islamic Azad University, Gorgan branch, Gorgan, Iran
7- Department of Biology, Islamic Azad University, Tehran Medical Branch, Tehran, Iran
8- Clinical Research Development Unit (CRDU) 5azar Hospital, Golestan University of Medical Sciences, Gorgan, Iran
9- Laboratory Sciences Research Center, Golestan University of Medical Sciences, Gorgan, Iran , joshaghani@goums.ac.ir
2- Infectious Diseases Research Center, Golestan University of Medical Sciences, Gorgan, Iran
3- Laboratory Sciences Research Center, Golestan University of Medical Sciences, Gorgan, Iran
4- Department of Medical Biotechnology, School of Allied Medical Sciences, Iran University of Medical Sciences, Tehran, Iran
5- Department of Hematology and Blood Banking, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran
6- Department of Microbiology, Islamic Azad University, Gorgan branch, Gorgan, Iran
7- Department of Biology, Islamic Azad University, Tehran Medical Branch, Tehran, Iran
8- Clinical Research Development Unit (CRDU) 5azar Hospital, Golestan University of Medical Sciences, Gorgan, Iran
9- Laboratory Sciences Research Center, Golestan University of Medical Sciences, Gorgan, Iran , joshaghani@goums.ac.ir
Abstract: (362 Views)
Background: Although public health interventions have slowed the spread of SARS CoV 2 infections, the worldwide pandemic of COVID 19 is progressing. Thus, effective and safe vaccination against SARS CoV 2 is an important tool for controlling the COVID 19 pandemic. Now in the early stages of COVID 19 vaccination, vaccinated individuals are interested in using antibody tests to confirm vaccination success and estimate the time of protection. Here, we assessed anti spike IgG responses in the general population 2 weeks after the second dose of the Sputnik V vaccine.
Methods: This study included blood samples of 67 individuals without a previous SARS CoV 2 infection taken 14 days after the second dose of the Sputnik V vaccine. Anti spike IgG responses were assessed with an enzyme linked immunosorbent assay (ELISA).
Results: Anti spike IgG was detected in 55 (82.1%) of 67 samples 14 days after the second dose of the Sputnik V vaccine. Antibody levels were significantly lower in males than in females, and 9 (75%) of 12 seronegative individuals were males.
Conclusion: Vaccination resulted in detectable anti spike IgG in 82.1% of individuals, and gender may be an important factor in the humoral response.
Methods: This study included blood samples of 67 individuals without a previous SARS CoV 2 infection taken 14 days after the second dose of the Sputnik V vaccine. Anti spike IgG responses were assessed with an enzyme linked immunosorbent assay (ELISA).
Results: Anti spike IgG was detected in 55 (82.1%) of 67 samples 14 days after the second dose of the Sputnik V vaccine. Antibody levels were significantly lower in males than in females, and 9 (75%) of 12 seronegative individuals were males.
Conclusion: Vaccination resulted in detectable anti spike IgG in 82.1% of individuals, and gender may be an important factor in the humoral response.
Research Article: Research Article |
Subject:
Virology
Received: 2022/06/15 | Accepted: 2022/08/10 | Published: 2024/01/15 | ePublished: 2024/01/15
Received: 2022/06/15 | Accepted: 2022/08/10 | Published: 2024/01/15 | ePublished: 2024/01/15
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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.