Volume 13, Issue 6 (Nov-Dec 2019)                   mljgoums 2019, 13(6): 1-10 | Back to browse issues page

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Abubakar S D. Characterization of Chromosomal Abnormalities in Cancer by Spectral Karyotyping. mljgoums. 2019; 13 (6) :1-10
URL: http://mlj.goums.ac.ir/article-1-1234-en.html
Ahmadu Bello University, Zaria, Nigeria , dsabubakar@abu.edu.ng
Abstract:   (118 Views)
        Spectral karyotyping is a novel method for the simultaneous visualization of the entire chromosomes of an organism by painting the chromosomes using a combination of fluorochromes. This allows improved identification of chromosomal aberrations that cannot be identified by conventional banding methods. Since introduction of cancer as a disease of the genome, researchers have employed various molecular techniques for a better understanding of malignancies. This review discusses the role and contributions of spectral karyotyping in the study and characterization of both solid and hematological malignancies.
        Keywords: Spectral karyotyping; Neoplasms; Chromosomes.
Full-Text [PDF 864 kb]   (48 Downloads)    
Type of Study: Systematic Review | Subject: Pathology
Received: 2019/07/27 | Accepted: 2019/09/4 | Published: 2019/10/30 | ePublished: 2019/10/30

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