fa تحقيقي Original Paper <div> <p><strong>ABSTRACT</strong></p> <p><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Background and Objective</strong>: Osteoporosis is one of the complications of diabetes. The aim of this study was to determine the impact of resistance training along with <em>Portulaca oleracea</em> supplementation on OPG and NF&kappa;B levels (bone markers) in women with type II diabetes.</p> <p><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Methods</strong>: Overall, 28 women with type II diabetes (44 to 60 years old) were randomly and equally assigned into four groups (supplement, training, training-supplement and control). An eight-week resistance training program (three one-hour sessions per week with one repetition maximum) was performed using three types of bands with different resistances, at 40-50% intensity and 50-70% maximum heart rate. <em>P. oleracea</em> seeds were supplemented daily (7.5 grams mixed in yogurt) for eight weeks. The data was analyzed using descriptive statistics, paired t-test and ANOVA.</p> <p><strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Results</strong>: After 8 weeks, OPG and NF&kappa;B levels in the three groups of supplement, training and training-supplement increased and decreased, respectively. The highest change in both variables was observed in the training-supplement group. Moreover, the level of these two variables in the training-supplement group had significant difference with the controls and other groups (P=0.000).</p> <p>&nbsp;<strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Conclusion</strong>: As a non-pharmacological therapeutic approach, the regular resistance training and <em>P. oleracea</em> supplementation can increase bone formation markers and reduce bone resorption in women with type II diabetes.</p> <p><strong>&nbsp;&nbsp; </strong></p> </div> Type II Diabetes, Resistance Training, Portulaca Oleracea, OPG, NFκB. 21 27 http://mlj.goums.ac.ir/browse.php?a_code=A-10-1-400&slc_lang=fa&sid=1 Shokufe Ziadloo 100319475328460010772 100319475328460010772 No Department of Exercise Physiology Parvin Farzanegi parvin.farzanegi@gmail.com 100319475328460010773 100319475328460010773 Yes Department of Exercise Physiology Masoumeh Habibian 100319475328460010774 100319475328460010774 No Department of Physical Education and Sports Sciences