Medical Laboratory Journal
Medical Laboratory Journal
mljgoums
Medical Sciences
http://mlj.goums.ac.ir
1
admin
2538-4449
10.52547/mlj
en
jalali
1399
6
1
gregorian
2020
9
1
14
5
online
1
fulltext
en
Activity of Iranian Medicinal Herbs against Human Intestinal Parasites (HIP): A Systematic Review
انگل شناسی
Parasitology
مروري
Review Article
<div><strong>Background and objectives:</strong> Intestinal parasitic infections are a major public health problem worldwide, especially in developing countries. It is estimated that around 3.5 billion people are infected with intestinal parasites. Human intestinal parasites (HIP) are clinically important due to broad epidemiological distribution, reinfection and drug resistance. In the last decades, bioactive compounds from herbs were used against a wide variety of microorganisms including parasites. We aimed to perform a systematic review on studies on the effects of medicinal herbs on HIPs in Iran.<br>
<br>
<strong> Methods:</strong> Relevant scientific publications until April, 2015 were extracted from five English databases (PubMed, Google Scholar, Ebsco, Science Direct and Scopus) and four Persian databases (Magiran, Irandoc, IranMedex and the Scientific Information Database).<br>
<br>
<strong> Results: </strong>A total of 18 papers and two <a name="OLE_LINK2"></a><a name="OLE_LINK1">dissertations</a> met the inclusion criteria. Overall, 22 different plant extracts were used against <em>Giardia lamblia</em>, <em>Entamoeba histolytica</em>, <em>Cryptosporidium</em> and <em>Hymenolepis nana</em>. Based on the results, the extracts could exert time- and dose-dependent inhibitory effects against the tested HIPs. Five plants types including <em>Allium</em>, <em>Chenopodium botrys, Carum copticum, F. asafoetida</em> and<em> Artemisia annua </em>were able to completely inhibit the tested parasites, while <em>Thymus vulgaris</em> and <em>A. paradoxum</em> showed the lowest inhibitory effect (7%).<br>
<br>
<strong> Conclusions:</strong> Given the findings, it is recommended to conduct in vivo studies on medicinal herbs with favorable in vitro effects against HIPs.</div>
Intestinal Parasites, Herbal Medicines, Plant Extracts, In vitro, In vivo
1
12
http://mlj.goums.ac.ir/browse.php?a_code=A-10-186-1&slc_lang=en&sid=1
Masoud
Soosaraei
masoudsoosaraie@gmail.com
100319475328460017973
100319475328460017973
No
Toxoplasmosis Research Center, Mazandaran University of Medical Sciences, Sari,Iran
Ahmad
Daryani
daryaanii1@yahoo.com
100319475328460017974
100319475328460017974
No
Toxoplasmosis Research Center, Mazandaran University of Medical Sciences, Sari,Iran
Shahabeddin
Sarvi
shahabe.saarvii@yahoo.com
100319475328460017975
100319475328460017975
No
Toxoplasmosis Research Center, Mazandaran University of Medical Sciences, Sari,Iran
Mohamad Taghi
Rahimi
rahimimt@gmail.com
100319475328460017976
100319475328460017976
No
School of Medical Science, Shahroud University of Medical Sciences, Shahroud, Iran
Mahdi
Fakhar
mahdif53@yahoo.com
100319475328460017977
100319475328460017977
No
Toxoplasmosis Research Center, Mazandaran University of Medical Sciences, Sari,Iran
Hajar
Ziaei Hezarjaribi
ziaei2000@yahoo.com
100319475328460017978
100319475328460017978
No
Toxoplasmosis Research Center, Mazandaran University of Medical Sciences, Sari,Iran
Mehdi
Sharif
msharifmathdsi@yahoo.com
100319475328460017979
100319475328460017979
Yes
Toxoplasmosis Research Center, Mazandaran University of Medical Sciences, Sari,Iran