fa فیزیولوژی ورزشی Sport Physiology تحقيقي Original Paper <div><strong>ABSTRACT</strong><br> <strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Background and Objectives:</strong> Apolipoprotein M (APOM) is a novel high-density lipoprotein (HDL)-associated protein involved in the production of pre-beta HDL and cholesterol efflux to HDL. The present study examined effect of 12 weeks of aerobic interval training on HDL-associated APOM levels.<br> <strong>&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</strong><strong>Methods:</strong> Study population included 20 healthy men aged 20 to 24 years. The subjects were randomly and equally divided into a training group and a control group. Each training session included 10 minutes of warm-up, 35 minutes of aerobic training (5 combined cycles each including four minutes of running at intensity of 85-95% and an active resting period of treadmill running at 65-75% of maximum heart rate for 3 minutes) and 10 minutes of cool-down. Blood samples (10 mL) were taken every four weeks. Two-way ANOVA and Bonferroni&#39;s post hoc test were used to compare the groups. A P-value of less than 0.05 was considered statistically significant.<br> <strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Results:</strong> At the end of the 12^th week, HDL-associated APOM levels increased in the training group and decreased in the control group. However, these changes were not statistically significant (P>0.05).&nbsp;<br> &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Conclusion:</strong> This study demonstrated that the 12-week aerobic interval training does not significantly affect HDL-associated APOM levels. However, it is recommended to monitor subjects&rsquo; diet throughout the study period to reach a more comprehensive conclusion.&nbsp;<br> &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Keywords:</strong> Aerobic interval training, Apolipoprotein M, Young men.<span dir="RTL"></span></div> Aerobic interval training, Apolipoprotein M, Young men. 1 5 http://mlj.goums.ac.ir/browse.php?a_code=A-10-637-2&slc_lang=fa&sid=1 Farzaneh Alirezaei 100319475328460015611 100319475328460015611 No Department of Exercise Biochemistry Divisiony, Faculty of Sports Sciences, University of Mazandaran, Babolsar, Iran Abbass Ghanbari-Niaki ghanbara@umz.ac.ir 100319475328460015612 100319475328460015612 Yes Exercise Biochemistry Division, Faculty of Sport Sciences, University of Mazandaran, Babolsar, Iran Hamidreza Joshaghani 100319475328460015613 100319475328460015613 No Laboratory Sciences Research Center, Golestan University of Medical Sciences, Gorgan, Iran Mehran Naghizadeh Ghomi 100319475328460015614 100319475328460015614 No Faculty of Mathematics, University of Mazandaran, Babolsar, Iran