Sat, Apr 20, 2024
Volume 15, Issue 3 (May-Jun 2021)
mljgoums 2021, 15(3): 27-32 |
Back to browse issues page
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Akha M H, Hashemvarzi S A. Investigating the Protective Effects of Endurance and Resistance Trainings on Serum level of Cellular and Vascular Adhesive Molecules in Obese Men. mljgoums 2021; 15 (3) :27-32
URL: http://mlj.goums.ac.ir/article-1-1300-en.html
URL: http://mlj.goums.ac.ir/article-1-1300-en.html
1- Department of Sports Physiology, Sari Branch, Islamic Azad University, Sari, Iran
2- Department of Sports Physiology, Sari Branch, Islamic Azad University, Sari, Iran , Hashemvarzi_tkd@yahoo.com
2- Department of Sports Physiology, Sari Branch, Islamic Azad University, Sari, Iran , Hashemvarzi_tkd@yahoo.com
Abstract: (4231 Views)
Background and objectives: The aim of this study was to compare the effect of an eight-weeks endurance and strength training on levels of cellular and vascular adhesion molecules in obese men.
Methods: Twenty-four obese volunteer men as subjects in this study were selected from Tehran and randomly assigned to control, endurance training, and strength training groups. The enduranBackground and objectives: Obesity, particularly abdominal obesity, is the most common cause of metabolic abnormalities, such as metabolic syndrome. The aim of this study was to compare effects of eight weeks of endurance and strength trainings on serum levels of cellular and vascular adhesion molecules in obese men.
Methods: Twenty-four obese men were randomly assigned to control, endurance training and strength training groups. The endurance training group performed a modified treadmill running protocol with an intensity of 50-70% of maximum heart rate. The resistance training included chest press, armpit stretch and leg and crus presses at intensity of 50-80% of one-repetition maximum. Serum levels of intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion protein 1 (VCAM--1) were measured using commercial ELISA kits. Data were analyzed by one-way ANOVA and post hoc Tukey test at significance of 0.05.
Results: Serum VCAM-1 and ICAM-1 levels decreased significantly in both training groups compared to the control group (P=0.0001). The reduction of serum VCAM-1 and ICAM-1 levels was more significant in the endurance training group than in the resistance training group.
Conclusion: Given the favorable effects of endurance and resistance trainings on serum levels of VCAM-1 and ICAM-1, the eight-week training could be performed as a protective intervention in obese people.ce training group performed a modified running protocol with an exercise intensity of 50% to 70% of HRmax on the treadmill. Resistance exercises also included chest press, armpit stretch, and leg and crus presses. The training intensity was 50% to 80% of 1-RM. Serum levels of VCAM-1 and ICAM-1 were measured using ELISA commercial kits. Data were analyzed by One-way ANOVA and post hoc Tukey at the significant level P<0.05.
Results: VCAM-1 and ICAM-1 levels decreased significantly in training groups compared to the control (P = 0.0001). Significant differences were also found between the values of VCAM-1 and ICAM-1 in the endurance training group compared to the resistance training group (P = 0.0001).
Conclusion: Overall, the levels of molecules showed that the values of VCAM-1 and ICAM-1 decreased significantly in the exercise group compared to the control group, but this decrease was more significant in the endurance training group. Therefore, it seems that 8 weeks of training in obese people can be very useful and prevent many diseases.
Methods: Twenty-four obese volunteer men as subjects in this study were selected from Tehran and randomly assigned to control, endurance training, and strength training groups. The enduranBackground and objectives: Obesity, particularly abdominal obesity, is the most common cause of metabolic abnormalities, such as metabolic syndrome. The aim of this study was to compare effects of eight weeks of endurance and strength trainings on serum levels of cellular and vascular adhesion molecules in obese men.
Methods: Twenty-four obese men were randomly assigned to control, endurance training and strength training groups. The endurance training group performed a modified treadmill running protocol with an intensity of 50-70% of maximum heart rate. The resistance training included chest press, armpit stretch and leg and crus presses at intensity of 50-80% of one-repetition maximum. Serum levels of intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion protein 1 (VCAM--1) were measured using commercial ELISA kits. Data were analyzed by one-way ANOVA and post hoc Tukey test at significance of 0.05.
Results: Serum VCAM-1 and ICAM-1 levels decreased significantly in both training groups compared to the control group (P=0.0001). The reduction of serum VCAM-1 and ICAM-1 levels was more significant in the endurance training group than in the resistance training group.
Conclusion: Given the favorable effects of endurance and resistance trainings on serum levels of VCAM-1 and ICAM-1, the eight-week training could be performed as a protective intervention in obese people.ce training group performed a modified running protocol with an exercise intensity of 50% to 70% of HRmax on the treadmill. Resistance exercises also included chest press, armpit stretch, and leg and crus presses. The training intensity was 50% to 80% of 1-RM. Serum levels of VCAM-1 and ICAM-1 were measured using ELISA commercial kits. Data were analyzed by One-way ANOVA and post hoc Tukey at the significant level P<0.05.
Results: VCAM-1 and ICAM-1 levels decreased significantly in training groups compared to the control (P = 0.0001). Significant differences were also found between the values of VCAM-1 and ICAM-1 in the endurance training group compared to the resistance training group (P = 0.0001).
Conclusion: Overall, the levels of molecules showed that the values of VCAM-1 and ICAM-1 decreased significantly in the exercise group compared to the control group, but this decrease was more significant in the endurance training group. Therefore, it seems that 8 weeks of training in obese people can be very useful and prevent many diseases.
Keywords: Endurance Training [MeSH], Resistance Training [MeSH], Intercellular Adhesion Molecule-1 [MeSH], Vascular Cell Adhesion Molecule-1 [MeSH], Obesity [MeSH]
Research Article: Original Paper |
Subject:
Sport Physiology
Received: 2020/06/5 | Accepted: 2020/08/5 | Published: 2021/04/28 | ePublished: 2021/04/28
Received: 2020/06/5 | Accepted: 2020/08/5 | Published: 2021/04/28 | ePublished: 2021/04/28
References
1. Souri R, Ravasi AA, Ranjbar K. Comparison of endurance and resistance training effects on serum levels of vaspin and adiponectin in obese middle-aged men. Sports Physiol. 2013; 5(20): 97-114. [Persian]
2. Grundy SM, Cleeman JI, Merz CN, Brewer HB, Clark LT, Hunninghake DB, et al. Coordinating Committee of the National Cholesterol Education Program. Implications of recent clinical trials for the national cholesterol education program adult treatment panel III guidelines. J Am Coll Cardiol. 2004; 44(3):720-32. [DOI] [PubMed] [Google Scholar]
3. Benatti FB, Junior AH. Leptin and endurance exercise: implications of adiposity and insulin. Rev Bras Med Esporte. 2007; 13(4):239E-44E. [DOI:10.1590/S1517-86922007000400011] [Google Scholar]
4. Cho JK, Han TK, Kang HS. Combined effects of body mass index and cardio/respiratory fitness on serum vaspin concentrations in Korean young men. Eur J Appl Physiol. 2010; 108(2):347. [DOI:10.1007/s00421-009-1238-8] [PubMed] [Google Scholar]
5. Kelly AS, Steinberger J, Olson TP, Dengel DR. In the absence of weight loss, exercise training does not improve adipokines or oxidative stress in overweight children. Metab. 2007; 56(7): 1005-9. [DOI:10.1016/j.metabol.2007.03.009] [Google Scholar]
6. Fatouros IG, Chatzinikolaou A, Tournis S, Nikolaidis MG, Jamurtas AZ, Douroudos II, et al. Intensity of resistance exercise determines adipokine and resting energy expenditure responses in overweight elderly individuals. Diabetes care. 2009; 32(12): 2161-7. [DOI:10.2337/dc08-1994.] [PubMed] [Google Scholar]
7. Ziccardi P, Nappo F, Giugliano G, Esposito K, Marfella R, Cioffi M, et al. Reduction of inflammatory cytokine concentrations and improvement of endothelial functions in obese women after weight loss over one year. Circ. 2002; 105(7):804-9. doi.org/10.1161/hc0702.104279. [DOI:10.1161/hc0702.104279] [PubMed] [Google Scholar]
8. Jalaly L, Sharifi G, Faramarzi M, Nematollahi A, Rafieian-Kopaei M, Amiri M, et al. Comparison of the effects of Crataegus oxyacantha extract, aerobic exercise and their combination on the serum levels of ICAM-1 and E-Selectin in patients with stable angina pectoris. DARU J Pharm Sci. 2015; 23(1):54. [DOI:10.1186/s40199-015-0137-2] [PubMed] [Google Scholar]
9. Wang Z, Nakayama .1155/2010T. Inflammation, a link between obesity and cardiovascular disease. Mediators Inflamm. 2010; 2010. [DOI:10.1155/2010/535918] [Google Scholar]
10. Basu A, Du M, Leyva MJ, Sanchez K, Betts NM, Wu Mو et al. Blueberries decrease cardiovascular risk factors in obese men and women with metabolic syndrome. J Nutr. 2010; 140(9): 1582-7. [DOI:10.3945/jn.110.124701] [PubMed] [Google Scholar]
11. Zoppini G, Targher G, Zamboni C, Venturi C, Cacciatori V, Moghetti P, et al. Effects of moderate-intensity exercise training on plasma biomarkers of inflammation and endothelial dysfunction in older patients with type 2 diabetes. Nutr metab cardiovasc dis. 2006; 16(8): 543-9. [DOI:10.1016/j.numecd.2005.09.004] [PubMed] [Google Scholar]
12. Hammett CJ, Prapavessis H, Baldi JC, Varo N, Schoenbeck U, Ameratunga R, et al. Effects of exercise training on 5 inflammatory markers associated with cardiovascular risk. Am Heart J. 2006; 151(2):367-e7. doi.org/10.1016/j.ahj.2005.08.009. [DOI:10.1016/j.ahj.2005.08.009] [PubMed] [Google Scholar]
13. Ding YH, Young CN, Luan X, Li J, Rafols JA, Clark JC. et al. Exercise preconditioning ameliorates inflammatory injury in ischemic rats during reperfusion. Acta Neuropathol. 2005; 109(3):237-46. [DOI:10.1007/s00401-004-0943-y] [PubMed] [Google Scholar]
14. Park JK, Schwarz N, Willoughby D, Koh Yunsuk. Acute changes in soluble cell adhesion molecules following different intensities of resistance exercise. Int J Sports Sci. 2015; 5(6):234-9. [View at Publisher]
15. Ghahramanloo E, Agha Ali Nejad H, Qarakhanlu R. Comparison of the effect of three types of strength training, endurance, and parallel (strength and endurance combination) on bioenergetic characteristics, maximum strength and physical composition of untrained men. Olympics. 2007; 40(14): 45-58. [Persian]
16. Tofighi A, Ghafari G. Effect of aerobic training with Omega-3 consumption on soluble adhesion molecules in the obese women. Majallah-i pizishki-i Danishgah-i Ulum-i Pizishki va Khadamat-i Bihdashti-i Darmani-i Tabriz. 2014; 36(1):20. [View at Publisher] [Google Scholar]
17. Silva RA, Almeida FM, Olivo CR, Saraiva‐Romanholo BM, Martins MA, Carvalho CR. Exercise reverses OVA‐induced inhibition of glucocorticoid receptor and increases anti‐inflammatory cytokines in asthma. Scand J Med Sci Sports. 2016; 26(1):82-92. doi.org/10.1111/sms.12411. [DOI:10.1111/sms.12411] [PubMed] [Google Scholar]
18. Conraads VM, Beckers P, Bosmans J, De Clerck LS, Stevens WJ, Vrints CJ, et al. Combined endurance/resistance training reduces plasma TNF-α receptor levels in patients with chronic heart failure and coronary artery disease. Eur Heart J. 2002; 23(23):1854-60. doi.org/10.1053/euhj.2002.3239. [DOI:10.1053/euhj.2002.3239] [PubMed] [Google Scholar]
19. Rosety I, Pery MT, Rosety J, García N, Rodríguez-Pareja MA, Brenes-Martín F, et al. Circuit resistance training improved endothelial dysfunction in obese aged women. Nutr Hosp. 2016; 33(1):131-4. [DOI:10.20960/nh.17] [PubMed] [Google Scholar]
20. Ryan AS, Ge S, Blumenthal JB, Serra MC, Prior SJ, Goldberg AP. Aerobic exercise and weight loss reduce vascular markers of inflammation and improve insulin sensitivity in obese women. J Am Geriatr Soc. 2014; 62(4):607-14. doi.org/10.1111/jgs.12749. [DOI:10.1111/jgs.12749] [PubMed] [Google Scholar]
Send email to the article author
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
Enamad
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.