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mljgoums 2018, 12(4): 29-35 |
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Alsabah Alavizadeh N, Hejazi K, Mabhout Moghadam T. Effects of Eight Weeks of Aerobic Exercise on Visfatin, Homocystein, C - reactive protein and Lipid Profile in Sedentary Men. mljgoums 2018; 12 (4) :29-35
URL: http://mlj.goums.ac.ir/article-1-1096-en.html
URL: http://mlj.goums.ac.ir/article-1-1096-en.html
1- Department of Sport Physiology, Human Sciences Faculty, Zahedan Branch, Islamic Azad University, Zahedan, Iran , alavizade80@yahoo.com
2- Department of Sport Physiology, Faculty of Physical Education and Sports Sciences, Toos Institute of Higher Education, Mashhad, Iran
3- Civil engineering and environment Department, Physical Education & Sport Sciences Faculty, Khavaran Institute of Higher Education, Mashhad, Iran
2- Department of Sport Physiology, Faculty of Physical Education and Sports Sciences, Toos Institute of Higher Education, Mashhad, Iran
3- Civil engineering and environment Department, Physical Education & Sport Sciences Faculty, Khavaran Institute of Higher Education, Mashhad, Iran
Abstract: (15815 Views)
ABSTRACT
Background and objectives: Visfatin is a newly characterized adipokine, which is highly expressed in visceral adipose tissue. The aim of this study was to evaluate effects of aerobic exercise training on visfatin, homocystein, C-reactive protein and lipid profile in sedentary men.
Methods: In this quasi-experimental study, 27 sedentary men were selected by convenience sampling method. The subjects were divided into a control group (n=13) and an aerobic training group (n=14). The subjects in the experimental group performed 60 minutes of aerobic exercise at 75-85% of maximum heart rate, three sessions per week for eight weeks. Data were analyzed in SPSS 16.0 (SPSS Inc., Chicago, IL, USA) using paired and independent sample t-test for comparison of means within and between groups, respectively. A P-value of less than 0.05 was considered statistically significant.
Results: The eight-week aerobic exercise training significantly reduced body weight (P=0.02), body mass index (P=0.01) and low-density lipoprotein-cholesterol (P=0.03) levels. It also caused a significant increase in the high-density-lipoprotein-cholesterol (P=0.00) and a significant decrease in visfatin levels (P=0.005). Serum homocysteine and C-reactive protein levels decreased by the end of the training program, but these changes were not statistically significant (P>0.05).
Conclusion: The eight-week aerobic exercise program could effectively improve lipid profile and visfatin levels. Therefore, this type of exercise could be recommended for prevention of cardiovascular disease and improvement of its risk factors.
Keywords: Aerobic, C-reactive protein, Exercise, Homocysteine.
Background and objectives: Visfatin is a newly characterized adipokine, which is highly expressed in visceral adipose tissue. The aim of this study was to evaluate effects of aerobic exercise training on visfatin, homocystein, C-reactive protein and lipid profile in sedentary men.
Methods: In this quasi-experimental study, 27 sedentary men were selected by convenience sampling method. The subjects were divided into a control group (n=13) and an aerobic training group (n=14). The subjects in the experimental group performed 60 minutes of aerobic exercise at 75-85% of maximum heart rate, three sessions per week for eight weeks. Data were analyzed in SPSS 16.0 (SPSS Inc., Chicago, IL, USA) using paired and independent sample t-test for comparison of means within and between groups, respectively. A P-value of less than 0.05 was considered statistically significant.
Results: The eight-week aerobic exercise training significantly reduced body weight (P=0.02), body mass index (P=0.01) and low-density lipoprotein-cholesterol (P=0.03) levels. It also caused a significant increase in the high-density-lipoprotein-cholesterol (P=0.00) and a significant decrease in visfatin levels (P=0.005). Serum homocysteine and C-reactive protein levels decreased by the end of the training program, but these changes were not statistically significant (P>0.05).
Conclusion: The eight-week aerobic exercise program could effectively improve lipid profile and visfatin levels. Therefore, this type of exercise could be recommended for prevention of cardiovascular disease and improvement of its risk factors.
Keywords: Aerobic, C-reactive protein, Exercise, Homocysteine.
Research Article: Original Paper |
Received: 2018/06/3 | Accepted: 2018/06/3 | Published: 2018/06/3 | ePublished: 2018/06/3
Received: 2018/06/3 | Accepted: 2018/06/3 | Published: 2018/06/3 | ePublished: 2018/06/3
References
1. Sasaki JE, MGd Santos. The role of aerobic exercise on endothelial function and on cardiovascular risk factors. Arquivos brasileiros de cardiologia, 2006; 87(5): e226-e231. [DOI:10.1590/S0066-782X2006001800036]
2. Campbell, PT, Campbell, KL, Wener, MH, Wood, BL, Potter, JD, McTiernan, A, et al., A yearlong exercise intervention decreases CRP among obese postmenopausal women. Medicine and science in sports and exercise, 2009. 41(8):1-10. [DOI:10.1249/MSS.0b013e31819c7feb]
3. Dahl TB, Yndestad A, Skjelland M, Øie E, Dahl A, Michelsen A, Damås JK., et al., Increased expression of visfatin in macrophages of human unstable carotid and coronary atherosclerosis: possible role in inflammation and plaque destabilization. Circulation, 2007. 115(8): p. 972-980. [DOI:10.1161/CIRCULATIONAHA.106.665893]
4. Lee, K.-J. Shin,YA, Young Lee, K, Jun, TW, Song, W, et al., Aerobic exercise training-induced decrease in plasma visfatin and insulin resistance in obese female adolescents. International journal of sport nutrition and exercise metabolism, 2010. 20(4): p. 275-281. [DOI:10.1123/ijsnem.20.4.275]
5. Kleinz, M.J. and A.P. Davenport, Immunocytochemical localization of the endogenous vasoactive peptide apelin to human vascular and endocardial endothelial cells. Regulatory peptides, 2004. 118(3): p. 119-125. [DOI:10.1016/j.regpep.2003.11.002]
6. Lau DC, Dhillon B, Yan H, Szmitko PE, Verma S., Adipokines: molecular links between obesity and atheroslcerosis. American Journal of Physiology-Heart and Circulatory Physiology, 2005. 288(5): p. H2031-H2041. [DOI:10.1152/ajpheart.01058.2004]
7. Abbasi F, Brown BW, Lamendola C, McLaughlin T, Reaven GM.., Relationship between obesity, insulin resistance, and coronary heart disease risk. Journal of the American College of Cardiology, 2002. 40(5): p. 937-943. [DOI:10.1016/S0735-1097(02)02051-X]
8. Seo, D, Young So,Y, Ha,S, Jung Yoo,E, Kim, D, Singh, H., Effects of 12 weeks of combined exercise training on visfatin and metabolic syndrome factors in obese middle-aged women. Journal of sports science & medicine, 2011. 10(1): p. 222.
9. Heald AH, Anderson SG, Ivison F, Laing I, Gibson JM, Cruickshank K., C-reactive protein and the insulin-like growth factor (IGF)-system in relation to risk of cardiovascular disease in different ethnic groups. Atherosclerosis, 2003. 170(1): p. 79-86. [DOI:10.1016/S0021-9150(03)00235-1]
10. Lopez, L, Peralta, CA, Lee, A, Aiello, A, Haan, MN, C-Reactive Protein (CRP) and the Prediction of Cardiovascular Death Among Mexican-Americans. Circulation, 2012. 125(10): p. AP148-150.
11. Greenlund, K., Plasma Homocysteine Distribution and Its Association With Parental History of Coronary Artery Disease in Black and White Children. The Bogalusa Heart Study Circulation, 1999. 99: p. 2144-2149. [DOI:10.1161/01.CIR.99.16.2144]
12. Dehghanpisheh Sh, Daryanoosh F, Jafari H, Mehrabani D, Kooshki M, Yaghikosh M, Effect of 8 weeks of aerobic training on serum level of visfatin and TNF-α in non-athletic young women. Journal of Gorgan University of Medical Sciences, 2014;16(3):5-15.
13. Kargarfard, M, Shariat, A, Shaw, I, Haddadi, P, Brandon S., Effects of Resistance and Aerobic Exercise Training or Education Associated with a Dietetic Program on Visfatin Concentrations and Body Composition in Overweight and Obese Women. Asian Journal of Sports Medicine, 2017;8(4):1-10. [DOI:10.5812/asjsm.57690]
14. Khanna, D., Effects of Diet and Exercise-Induced Weight Loss in Sedentary Obese Women on Inflammatory Markers, Resistin, and Visfatin. J Nutr Obes, 2017. 1(1): p. 1-13.
15. Banaeifar, A, Rahmanimoghadam, N, Zafari, A, Kazemzade, Y., Effect of 12 weeks of aerobic training on visfatin levels in obese women. European Journal of Experimental Biology, 2012. 2(6): p. 2293-2296.
16. Sternfeld, B., Ainsworth, BE, Quesenberry JR, Physical activity patterns in a diverse population of women. Preventive medicine, 1999. 28(3): p. 313-323. [DOI:10.1006/pmed.1998.0470]
17. Alavizadeh, N. Hejazi, K, Mabhot Moghadam, T. Effect of aerobic exercise with 75-85% of maximum heart rate on apelin and insulin resistance index in sedentary men. The Horizon of Medical Sciences, 2017. 23(1): p. 55-61. [DOI:10.18869/acadpub.hms.23.1.55]
18. Borg, G., Borg's perceived exertion and pain scales. 1998: Human kinetics.
19. Seifi, L., F. Daryanoosh, Samadi, M. The effect of 12 weeks aerobic exercise training on visfatin, chemerin serum changes in 45-60 year old obese women with type2 diabetes. Journal of Shahid Sadoughi University of Medical Sciences, 2016. 24(1): p. 55-64.
20. Taghian, F., Zolfaghary, M, Hedayati, M. Effect of 12 weeks aerobic exercise on Visfatin level and insulin resistance in obese women. Razi Journal of Medical Sciences, 2014. 20(116): p. 35-44.
21. Giti, Z, Hosseini, S.A, Nourizadeh, R, Edalat Manesh, M.A, Noura, M, Robati, R., The Effect of Aerobic Training on Visfatin, Total Cholesterol and High Density Lipoprotein of Middle Age Females. 2011.
22. Choi, KM, Kim, JH, Cho, GJ, Baik, SH, Park, HS, Kim, SM., Effect of exercise training on plasma visfatin and eotaxin levels. European Journal of Endocrinology, 2007. 157(4): p. 437-442. [DOI:10.1530/EJE-07-0127]
23. Berndt, J1, Klöting, N, Kralisch, S, Kovacs, P, Fasshauer, M, Schön, MR, et al., Plasma visfatin concentrations and fat depot–specific mRNA expression in humans. Diabetes, 2005. 54(10): p. 2911-2916. [DOI:10.2337/diabetes.54.10.2911]
24. Mogharnasi, M., A. Gaeini, Sheikholeslami Vatani, D. Comparing the effects of two training methods of aerobic and anaerobic on some pre-inflammatory cytokines in adult male rats. Iranian Journal of Endocrinology and Metabolism, 2010. 11(2): p. 191-198.
25. Kamal, N.N, Ragy, M.M. The effects of exercise on C-reactive protein, insulin, leptin and some cardiometabolic risk factors in Egyptian children with or without metabolic syndrome. Diabetology & metabolic syndrome, 2012. 4(1): p. 27. [DOI:10.1186/1758-5996-4-27]
26. Campbell, KL, Campbell, PT, Ulrich, CM, Wener, M, Alfano, CM, Foster-Schubert, K. et al., No reduction in C-reactive protein following a 12-month randomized controlled trial of exercise in men and women. Cancer Epidemiology and Prevention Biomarkers,2008;17(7): 1714-1718. [DOI:10.1158/1055-9965.EPI-08-0088]
27. Di Santolo, M, Banfi, G, Stel, G, Cauci, S. Association of recreational physical activity with homocysteine, folate and lipid markers in young women. European journal of applied physiology, 2009. 105(1): p. 111-118. [DOI:10.1007/s00421-008-0880-x]
28. Joubert, L.M, Manore, M.M. Exercise, Nutrition, and homocysteine. International journal of sport nutrition and exercise metabolism, 2006. 16(4): p. 341-361. [DOI:10.1123/ijsnem.16.4.341]
29. Bonow, R.O. Braunwald's Heart Disease E-Book: A Textbook of Cardiovascular Medicine. Elsevier Health Sciences. 2011
30. Choubineh, S., V. Dabidi Roshan, Gaeini, A. The effect of two methods of continuous and interval aerobic trainings on hs-CRP levels in wistar rats. Journal of movement science and sport, 2007. 5(9): p. 1-13.
31. Genest, J., C-reactive protein: risk factor, biomarker and/or therapeutic target? Canadian Journal of Cardiology, 2010. 26: p. 41A-44A. [DOI:10.1016/S0828-282X(10)71061-8]
32. Nowak, R., D. Kstrzewa-Nowak, M, Eider, J. Does aerobic exercise have a beneficial effect on plasma lipid profile in young soccer players? Trends in Sport Sciences, 2015. 22(3):14-28
33. Monazamnezhad, A., et al., The effects of aerobic exercise on lipid profile and body composition in women with multiple sclerosis. Jundishapur Journal of Chronic Disease Care, 2015. 4(1):1-10. [DOI:10.5812/jjcdc.26619]
34. Kazemi, A. Shahrokhi, K. The Effect of 8 Weeks of HIT Workouts Plasma Levels of TNF-a, IL-6 and Lipid Profile in Overweight Children. Journal of Knowledge & Health, 2016. 11(2): p. 24-31.
35. Aggarwala, J., Effects of aerobic exercise on blood glucose levels and lipid profile in Diabetes Mellitus type 2 subjects. Ameen J Med Sc 2016. 9(1): p. 65-69.
36. Sardar, M., Gaeini, A, Ramezani, J. The effect of 8-weeks of regular physical activity on blood glucose, body mass index, maximal oxygen uptake (Vo2max) and risk factors cardiovascular diseases in patients with type of 1 diabetes mellitus. Iranian Journal of Endocrinology and Metabolism, 2008. 10(2): p. 91-97.
37. Ha, C.-H. So, W-Y. Effects of combined exercise training on body composition and metabolic syndrome factors. Iranian journal of public health, 2012. 41(8): p. 20.
38. Ward, JR, Wilson, HL, Francis, SE, Crossman, DC, Sabroe, I. Translational Mini-Review Series on Immunology of Vascular Disease: Inflammation, infections and Toll-like receptors in cardiovascular disease. Clinical & Experimental Immunology, 2009. 156(3): p. 386-394. [DOI:10.1111/j.1365-2249.2009.03886.x]
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