en باکتری شناسی bacteriology Research Article Research Article <span style="font-size:11pt"><span style="line-height:150%"><span calibri="" style="font-family:"><b><span lang="EN" style="font-size:12.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">Objectives:</span></span></span></b><span lang="EN" style="font-size:12.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times=""> Nosocomial infection is among the most concerning issues among hospitalized patients. The present study investigated the frequency of bacterial infections and their antibiotic resistance pattern among hospitalized patients in the dermatology ward. </span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:150%"><span calibri="" style="font-family:"><b><span lang="EN" style="font-size:12.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">Methods:</span></span></span></b><span lang="EN" style="font-size:12.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times=""> This cross-sectional study was conducted on patients admitted to the dermatology ward in Razi Hospital, Rasht, Iran, between 2018 and 2022. Demographical data and clinical characteristics of the 34 patients with bacterial infections were recorded and analyzed. The bacterial isolates were collected from the skin and soft tissue, </span></span></span><span style="font-size:12.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">urinary tract</span></span></span><span lang="EN" style="font-size:12.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">, or bloodstream infections, and the clinical findings and outcomes of the patients were recorded.</span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:150%"><span calibri="" style="font-family:"><b><span lang="EN" style="font-size:12.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">Results:</span></span></span></b><span lang="EN" style="font-size:12.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times=""> Thirty-four patients had positive results for bacterial culture. </span></span></span><span style="font-size:12.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">The mean age of the patients was 53.56&plusmn;17.14 years, and 61.8% were female. The most frequent origin of the infection was the urinary tract. </span></span></span><i><span lang="EN" style="font-size:12.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">Staphylococcus epidermidis </span></span></span></i><span lang="EN" style="font-size:12.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">(<i>S. epidermidis</i>)<i> </i>and <i>Klebsiella</i> spp. were more prevalent isolates.</span></span></span> <i><span lang="EN" style="font-size:12.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">Klebsiella</span></span></span></i><span lang="EN" style="font-size:12.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times=""> spp.</span></span></span><span style="font-size:12.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times=""> and </span></span></span><i><span lang="EN" style="font-size:12.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">Escherichia coli </span></span></span></i><span lang="EN" style="font-size:12.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">(<i>E. coli</i>) </span></span></span><span style="font-size:12.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">were more common in patients aged <56 years and &ge;56 years, respectively, and among &ge;13 days and <13 days of hospitalization, respectively<i>.</i> <a name="_Hlk167176116">Antibiotic resistance were high in </a></span></span></span><i><span lang="EN" style="font-size:12.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">S. epidermidis</span></span></span></i> <span style="font-size:12.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">and </span></span></span><i><span lang="EN" style="font-size:12.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">Pseudomonas aeruginosa </span></span></span></i><span lang="EN" style="font-size:12.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">(<i>P.</i> <i>aeruginosa</i>)isolates, where </span></span></span><span style="font-size:12.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">showed resistance to all antibiotics.</span></span></span><span lang="EN" style="font-size:12.0pt"><span style="line-height:150%"><span style="font-family:"Times New Roman",serif"></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:150%"><span calibri="" style="font-family:"><b><span lang="EN" style="font-size:12.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">Conclusion:</span></span></span></b> <span style="font-size:12.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">This study revealed significant patterns of bacterial infections and antibiotic resistance in dermatology ward patients with <i>E. coli</i> and <i>Klebsiella</i> spp. Predominant in urinary tract infections and a diverse profile in skin and soft tissue infections. </span></span></span><b><span lang="EN" style="font-size:12.0pt"><span style="line-height:150%"><span style="font-family:"Times New Roman",serif"></span></span></span></b></span></span></span> Bacterial infection, Urinary tract infection, Antibiotic resistance pattern, Soft tissue infection 0 0 http://mlj.goums.ac.ir/browse.php?a_code=A-10-1772-1&slc_lang=en&sid=1 Hadi Hadi Seddigh Ebrahim-Saraei Seddigh.hadi@gmail.com 100319475328460033034 100319475328460033034 No Guilan University of Medical Sciences, Rasht, Iran Tofigh Yaghoubi bmed.sciences@gmail.com 100319475328460033035 100319475328460033035 No Guilan University of Medical Sciences, Rasht, Iran Zeynab Fathalizadeh biomedscience88@gmail.com 100319475328460033036 100319475328460033036 No Guilan University of Medical Sciences, Rasht, Iran Masoumeh Pourmohammadi nasi202023@yahoo.com 100319475328460033037 100319475328460033037 No Guilan University of Medical Sciences, Rasht, Iran. Hojat Eftekhari hojat.eftekhari.derm@gmail.com 100319475328460033038 100319475328460033038 Yes Guilan University of Medical Sciences, Rasht, Iran