en ميکروب شناسي Microbiology تحقيقي Original Paper <strong>Objectives:</strong> Although extrapulmonary tuberculosis (EPTB) is a secondary target for national TB control programs, its significance has increased worldwide. In order to study the epidemiology of EPTB in the Northeast of Iran, this survey was conducted.<br> <strong>Methods</strong> <strong>and Methods:</strong> A population-based, retrospective analysis of all cases of EPTB during 2012&ndash;2015 reported to the TB Unit of the Golestan was performed. Socioeconomic and environmental variables, sites, admission, mode of diagnosis and outcome status were collected. Data analyzed through SPSS 25.0 by descriptive and analytical statistical methods.<br> <strong>Results:</strong> A total of 741 cases of EPTB were included. Patients were mainly female (59.1%), age of 0 to 40 years old (57.6%), less than five years of education (46.7%) and mainly Fars (39.6%). Non-native ethnicities significantly acquired EPTB more than native ethnicities (p<0.001). Mortality rate was 5.1%. Smoking detected more frequently in EPTB patients (p<0.001). HIV status of most EPTB patients (89.3%) were unknown. The most common forms were pleural (30.5%) and lymphadenopathy (22.0%). Cultures and PCR performed in only about 10 percent of EPTB patients in our study.<br> <strong>Conclusions:</strong> EPTB was more prevalent in non-native population. Improvement of socioeconomic conditions and screening program may be successful in reducing the problem among immigrant extrapulmonary tuberculosis, epidemiology, immigration, Iran 1 7 http://mlj.goums.ac.ir/browse.php?a_code=A-10-26-6&slc_lang=en&sid=1 Alireza Nikonajad nikoonejad.anikoo@gmail.com 100319475328460018931 100319475328460018931 No Department of infectious disease, Faculty of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran Sadegh Ali Azimi drsazimi@yahoo.com 100319475328460018932 100319475328460018932 No Department of infectious disease, Faculty of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran. Abbas Allami allami@qums.ac.ir 100319475328460018933 100319475328460018933 Yes Department of infectious disease, Faculty of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran Reza Qasemi Bargi rqasemibarqi@yahoo.com 100319475328460018934 100319475328460018934 No Department of infectious disease, Faculty of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran. Alijan Tabarraei tabarraei@goums.ac.ir 100319475328460018935 100319475328460018935 No Infectious diseases research centre, Golestan University of Medical Sciences, Gorgan, Iran