Medical Laboratory Journal
Medical Laboratory Journal
mljgoums
Medical Sciences
http://mlj.goums.ac.ir
1
admin
2538-4449
10.52547/mlj
en
jalali
1386
7
1
gregorian
2007
10
1
1
2
online
1
fulltext
fa
مقایسه سطح هوموسیستئین، اسید فولیک و کوبالامین پلاسمای بیماران پس از سکته قلبی با افراد سالم در شهرستان گرگان
Plasma Level of Homocysteine, Folic acid and Cobalamine in Patients suffered from myocardial infarction
<p align="left"><b><font face="TimesNewRoman,Bold" size="3">Abstract</font></b></p>
<p align="left"><b><font face="TimesNewRoman,Bold" size="3">Introduction: </font></b></p>
<p align="left"><b><font face="TimesNewRoman,Bold" size="3">methionine. Many reports confirm the correlation between hyper</font></b></p>
<p align="left"><b><font face="TimesNewRoman,Bold" size="3">homocysteinemia and cardiovascular disease. This study was aimed</font></b></p>
<p align="left"><b><font face="TimesNewRoman,Bold" size="3">at determining the effect of B12 and folate deficiency on the</font></b></p>
<p align="left"><b><font face="TimesNewRoman,Bold" size="3">homocysteine level after myocardial infarction.</font></b></p>
<b><font face="TimesNewRoman" size="3">Homocysteine is produced by demethylation of</font></b>
<p align="left"><b><b><font face="TimesNewRoman,Bold" size="3">Materials and methods: </font></b></b></p>
<p align="left"><b><b><font face="TimesNewRoman,Bold" size="3">study were patients with myocardial infarction (N = 48) and healthy</font></b></b></p>
<p align="left"><b><b><font face="TimesNewRoman,Bold" size="3">patients (N = 48) Eliza method was used to assay Homocysteine and</font></b></b></p>
<p align="left"><b><b><font face="TimesNewRoman,Bold" size="3">RIA for folic acid and vitamin B12.</font></b></b></p>
<b><b><font face="TimesNewRoman" size="3">The subjects of This descriptive-analytic</font></b></b>
<p align="left"><b><b><b><font face="TimesNewRoman,Bold" size="3">Results: </font></b></b></b></p>
<p align="left"><b><b><b><font face="TimesNewRoman,Bold" size="3">(30.3 ± 5.3 μm/l) and the control group (11.1 ± 3.1) is significant (p<</font></b></b></b></p>
<p align="left"><b><b><b><font face="TimesNewRoman,Bold" size="3">0.001). There is no significant difference between Serum B12 in case</font></b></b></b></p>
<p align="left"><b><b><b><font face="TimesNewRoman,Bold" size="3">(297.1 ± 208.9 pm/l) and control group (261.5 ± 205.3) and it is true</font></b></b></b></p>
<p align="left"><b><b><b><font face="TimesNewRoman,Bold" size="3">about Serum folic acid of case (3.9 ± 2.9 ng/m) and control group</font></b></b></b></p>
<p align="left"><b><b><b><font face="TimesNewRoman,Bold" size="3">(4.3 ± 3.5). The homocysteine level of all patients and four of</font></b></b></b></p>
<p align="left"><b><b><b><font face="TimesNewRoman,Bold" size="3">healthy subjects is higher than normal. The folic acid Level of 11</font></b></b></b></p>
<p align="left"><b><b><b><font face="TimesNewRoman,Bold" size="3">patients and four healthy subjects is less than normal.</font></b></b></b></p>
<b><b><b><font face="TimesNewRoman" size="3">the difference between the homocysteine Level of the case</font></b></b></b>
<p align="left"><b><b><b><b><font face="TimesNewRoman,Bold" size="3">Conclusion: </font></b></b></b></b></p>
<p align="left"><b><b><b><b><font face="TimesNewRoman,Bold" size="3">of control group and this difference is not related to decrease of B12</font></b></b></b></b></p>
<p align="left"><b><b><b><b><font face="TimesNewRoman,Bold" size="3">Level, Physicians must pay attention to The other risk factors.</font></b></b></b></b></p>
<b><b><b><b><font face="TimesNewRoman" size="3">since the homocysteine level of patients is there times</font></b></b></b></b>
<p align="left"><b><b><b><b><b><font face="TimesNewRoman,Bold" size="3">Key words: </font></b></b></b></b></b></p>
<p><b><b><b><b><b><font face="TimesNewRoman,Bold" size="3">cobalamine, cardiovascular disease.</font></b></b></b></b></b></p>
<b><b><b><b><b><font face="TimesNewRoman" size="3">Folic acid, Homocysteine, Myocardial Infarction,</font></b></b></b></b></b>
Key words: Folic acid, Homocysteine, Myocardial Infarction, cobalamine, cardiovascular disease.
0
0
http://mlj.goums.ac.ir/browse.php?a_code=A-10-1-55&slc_lang=fa&sid=1
HR
Joshaghani
حمید رضا
جوشقانی
hr_joshaghani@yahoo.com
100319475328460013068
100319475328460013068
Yes
Associated professor of Biochemistry
دانشگاه علوم پزشکی گلستان
AA
Shirafcan
احمد علی
شیرافکن
100319475328460013069
100319475328460013069
No
،دانشگاه علوم پزشکی گلستان
AJ
Marjani
عبدالجلال
مرجانی
100319475328460013070
100319475328460013070
No
دانشگاه علوم پزشکی گلستان