Medical Laboratory Journal
Medical Laboratory Journal
mljgoums
Medical Sciences
http://mlj.goums.ac.ir
1
admin
2538-4449
10.52547/mlj
en
jalali
1399
2
1
gregorian
2020
5
1
14
3
online
1
fulltext
en
Evaluation of Aflatoxin M1 Level in Human Breast Milk samples from Jiroft, South of Iran
قارچ شناسی
Mycology
تحقيقي
Original Paper
<div><strong>Background and objective: </strong>Human breast milk is the primary food for newborns that possess all essential nutrients for their growth and health. However, breast milk can be contaminated with various toxins including aflatoxin M1 (AFM1), a hydroxylated metabolite of aflatoxin B1 formed in the liver and excreted into the breast milk. This toxin can have immunosuppressive, mutagenic, teratogenic and carcinogenic effects. The present study aimed to investigate the level of AFM1 in human breast milk samples from Jiroft (Kerman Province), Iran.<br>
<strong> Methods:</strong> A total of 84 human breast milk samples were collected from lactating mothers who were referred to number one clinic in Jiroft from April 2016 to January 2017. The level of AFM1 was measured using commercial enzyme-linked immunosorbent assay kits.<br>
<strong> Results:</strong> Aflatoxin M1 was detected in all (100%) human breast milk samples within the interval values of 3.2 to 8.8 ng/L (mean, 4.1±0.7 ng/L). The level of AFM1 in all samples was lower than the maximum tolerable limit (25 ng/L) suggested by the EU and the Codex Alimentarius Commission.<br>
<strong> Conclusion:</strong> Although AFM1 is present in all human breast milk samples from the city of Jiroft, the level of this toxin is within the tolerable limit. Therefore, it seems that infants are not at risk.</div>
Aflatoxin M1, Human breast milk, Infant
1
6
http://mlj.goums.ac.ir/browse.php?a_code=A-10-724-1&slc_lang=en&sid=1
Mohadeseh
Kamali
mehdimycology@gmail.com
100319475328460017990
100319475328460017990
No
Department of Internal Medicine, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran
Ali
Kamali
alikamali1348@yahoo.com
100319475328460017991
100319475328460017991
No
Department of Infectious Diseases, School of Medicine, Jiroft University of Medical Sciences, Jiroft, Iran
Mehdi
Taheri sarvtin
mehditaheri.mt@gmail.com
100319475328460017992
100319475328460017992
Yes
Department of Medical Mycology and Parasitology, School of Medicine, Jiroft University of Medical Sciences, Jiroft, Iran