RT - Journal Article T1 - Characterization of Chromosomal Abnormalities in Cancer by Spectral Karyotyping JF - mljgoums YR - 2019 JO - mljgoums VO - 13 IS - 6 UR - http://mlj.goums.ac.ir/article-1-1234-en.html SP - 1 EP - 10 K1 - Spectral karyotyping K1 - Neoplasms K1 - Chromosomes. AB - ABSTRACT Spectral karyotyping is a novel method for the simultaneous visualization of the entire chromosomes of an organism by painting the chromosomes using a combination of fluorochromes. This allows improved identification of chromosomal aberrations that cannot be identified by conventional banding methods. Since introduction of cancer as a disease of the genome, researchers have employed various molecular techniques for a better understanding of malignancies. This review discusses the role and contributions of spectral karyotyping in the study and characterization of both solid and hematological malignancies. Keywords: Spectral karyotyping; Neoplasms; Chromosomes. LA eng UL http://mlj.goums.ac.ir/article-1-1234-en.html M3 10.29252/mlj.13.6.1 ER -