Mansouri Ghiasi MA, Nasrollahi Omran A,Hashemi M,Rajab Zade Kanafi
P,Jahangiri Rad Manjili.[The Prevalenceof
Antibiotic Resistance Pattern of Staphylococcus Aureus
Isolated from Nasal Carriage of Surgical
Ward’s Staff in ShahidrajaeeHospital of Tonekabon,Iran]. MLJ. 2013; 7(1):
Mansouri Ghiasi, MA. (PhD)1, Nasrollahi Omran, A.(PhD)*2,
Hashemi, M.
(PhD)3, Rajab Zade Kanafi, P. (PhD)4, Jahangiri Rad Manjili,M (PhD)5
1.Assistant professor of Dermatologist, Deptartment of Dermatology, Faculty of Medicine, Islamic
Azad University of Tonekabon Branch , Tonekabon, Iran
2.Assistant professor of Microbiology, Department of
Microbiology, Faculty of Biology Sciences, Islamic Azad University of Tonekabon Branch, Tonekabon, Iran
3.Assistant professor of Microbiology, Department of
Microbiology, Faculty of Biology Sciences, Islamic Azad University of Tonekabon Branch, Tonekabon, Iran
4.Faculty of Medicine, Islamic Azad University of Tonekabon
Branch, Tonekabon,Iran
5.Faculty of Medicine, Islamic Azad University of Tonekabon
Branch, Tonekabon,Iran
Abstract
Background and Objective:Staphylococcus aureus is one of the important factors causing
nosocomial infections. Typically 25-30 percent of healthy people carry the
bacteria in their anterior nasal cavity. The Physicians(50%), nurses(70%)
and hospital staff (90%) are the
carriers of this bacteria, leading to the infection of inpatients. The Emergence of antibiotic-
resistant Staphylococcus strains esp. vancomycin and methicillin resistant has bring about several problem in treatment of the infections caused by
Staphylococcus strains. Hence, we aimed to study the frequency of
staphylococcus aureus carriers and resistance pattern among medical
personnel of the surgical ward in
ShahidRajaee hospital, Tonekabon.
Material and Methods: this analytic-descriptive study was conducted on the samples taken
from nasal carriage of medical staff of surgical ward (N=120). Antibiotic-
resistant of Staphylococcus strains were assessed by antibiogram
and disk diffusion (DAD), in accordance with CLSI standards.
Results: of 34 (28.33%) who are nasal carriers of
staphylococcus, 12 are over 30 years old and 24
under 30. Based on
antibiogram, 1.97% of specimens are
sensitive to Gentamicin and Co-trimoxazole , 1.94% to
ciprofloxacin, 2.88% to vancomycin and 6.20% to
Methicillin. In addition, 100% of specimens are resistant to Ampicillin, 1.97%
to penicillin and 2.88% to Amoxicillin.
Four isolates
are resistant both to methicillin and vancomycin.
Conclusion:In this study, the spectrum of S. aureus resistant and sensitive strains to some antibiotics
is similar to other studies, but a dramatic increase is seen in the rate of
MRSA and non-susceptible cases to vancomycin. The Effectiveness of Penicillin, Amoxicillin
and Ampicillin is still very low on S. aureus
samples.
Key words: Prevalance Resistance Pattern, Staphylococcus aureus,
Medical Staff, Nasal Cavity, Tonekabon
Corresponding Author: Nasrollahi Omran A
Email: Ayat51@yahoo.co.in
Received
26 May 2012Revised 5 Jan 2013Accepted 5 Jan 2013