This paper should be cited as:Esmaeili, R. Yousefi Mashouf, R. Moshtaghi, A. Alikhani, MY.

Frequency of Antibiotic Resistance Patterns in Bacteria Isolated from Children

Esmaeili, R1, Yousefi Mashouf, R. (PhD)2*, Moshtaghi, A. (MD)3, Alikhani, MY. (PhD)4

1. Student of Medicine, School of Medicine, Student's Research Committee, Hamadan University of Medical Sciences, Hamadan, Iran

2. Professor of Microbiology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran

3. Assistant Professor of Pediatrics , School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran

4. Associate professor of Microbiology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran

Abstract

Background and Objective: Bacterial infectioins in particular meningitis, pneumonia and septicemia are still some of the most causes of mortalities in children.The aim of present study was to identify the most common bacterial agents causing infectionis in children under 14 and detection of antibiotic resistance paterns.

Material and Methods: During two years,1897samples were obtained from the patients suspected bacterial infectioins. They were investigated for bacterial cultures, age, sex and antibiogram patterns. The species were identified by biochemical and serological methods.

Results:Of 1897 samples, 563 (29.6%) had positve bacterial culture.Of these 74.7% were gram negative and 25.3%gram positive.The most common species were Escherichia coli(34.1%), Staphylococcus aureus(17.1%),Psuedomonas aeroginosa (12.4%),Kelebsiella (11%) and Staphylococcus epidermidis(5.7%).The most effective antibiotics against both gram positive and gram negative bacteria were ceftriaoxne, nitrofurantoin, nalidixic acid, amikacin and gentamycin.

Conclusion:The gram negative bacteria in particular Escherichia coli, Psuedomonas aeroginosa and Kelebsiella are the predominant causes of bacterial infections in children under 14 in these regions. Most species showed a high relative resisitance to routine antibiotics such as ampicillin, trimethoprim and chloramphenicol.

Key Words: Bacteria;Infection; Children;Antibiotic

Corresponding Author:Yousefi Mashouf, R.

Email: yousefimash@yahoo.com

Received 16 Feb 2013 Revised 19 July 2013 Accepted 27 July 2013